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Elevated Adverse Outcomes in Black Pediatric Burn Patients
Joshua E Lewis1, Adannaya Ihediwa1, Jordan Kankam2
1John Sealy School of Medicine, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555-1317, United States.
Insights
African American pediatric burn patients face higher risks of mortality, infection, and graft failure. This study highlights racial disparities in burn care outcomes, emphasizing the need for targeted interventions to improve treatment for these vulnerable children.
Area of Science:
- Medical Research
- Pediatric Burn Care
- Health Disparities
Background:
- Pediatric burn injuries can lead to severe adverse outcomes.
- Emerging data indicate racial disparities affecting African American pediatric burn patients in U.S. hospitals.
- These disparities are linked to increased mortality, pain, complications, and infection susceptibility.
Purpose of the Study:
- To investigate the association between race and adverse outcomes in pediatric burn patients.
- To determine if African American pediatric burn patients experience a higher risk of negative health events post-injury.
Main Methods:
- Retrospective cohort study using the TriNetX Research Database.
- Inclusion of pediatric burn patients at 3 months, 6 months, and 1 year post-injury.
- Propensity score matching to create comparable cohorts (African American, White, Asian) based on demographics and burn severity.
Main Results:
- African American pediatric burn patients showed significantly higher risks of mortality (RR=1.218), hypertrophic scarring (RR=1.139), inhalation injury (RR=2.201), infection (RR=1.330), and graft failure (RR=2.090).
- African American patients were less likely to report pain (RR=0.662).
- Significant differences in outcomes were observed across racial cohorts.
Conclusions:
- African American children with burn injuries face elevated rates of adverse post-burn outcomes.
- Findings underscore the critical need for improved burn injury management strategies to mitigate risks and enhance patient outcomes in this population.
- Addressing racial disparities in pediatric burn care is essential for equitable health.
Abstract:
Pediatric patients with burn injuries often experience various adverse outcomes. Recently, disparities affecting African American pediatric patients with burn injuries within US hospitals have emerged. These disparities contribute to elevated adverse outcomes such as increased mortality, pain, severe complications, and higher susceptibility to infections posing significant health risks. This study aimed to analyze the relationship between race and elevated adverse outcomes in pediatric patients with burn injuries. We hypothesized that African American pediatric patients with burn injuries would experience an increased risk of adverse outcomes. This retrospective cohort study used the TriNetX Research Database. Pediatric patients with burn injuries who were followed at 3 months, 6 months, and 12 months postburn injury were included. Patients were divided into 3 cohorts based on race: African American (cohort A), White (cohort B), and Asian (cohort C). Propensity score matching was used to create comparable cohorts based on age, gender, ethnicity, and burn severity. The primary outcomes included mortality, pain, hypertrophic scarring, inhalation injury, infection, and graft failure. Significant differences in outcomes were found between the cohorts. African American patients with burn injuries had elevated risk of mortality (RR = 1.218, P = .0057), hypertrophic scarring (RR = 1.139, P < .0001), inhalation injury (RR = 2.201, P = .0338), infection (RR = 1.330, P = .0065), graft failure (RR = 2.090, P = .0003), and were less likely to report pain (RR = 0.662, P = .0001). African American patients in the pediatric population are associated with elevated rates of adverse postburn injury outcomes. These findings highlight the need for enhanced burn injury treatment to minimize risks and improve patient outcomes.
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