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Acupoint Application as a Traditional Chinese Medicine Treatment for Fatigue Associated with Chronic Obstructive Pulmonary Disease

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Internet-Based Behavioral Cough Suppression Therapy for Refractory Chronic Cough: A Randomized Controlled Trial.

Jane R Salois¹, Kassidi L Heinle¹, Laurie J Slovarp¹

¹School of Speech, Language, Hearing, & Occupational Sciences, University of Montana, Missoula.

American Journal of Speech-Language Pathology

|August 14, 2025

Summary

Internet-based behavioral cough suppression therapy (IBCST) effectively reduced chronic cough symptoms in adults. Participants reported high satisfaction with the convenient, online treatment, showing significant improvements in quality of life.

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Area of Science:

Digital therapeutics
Behavioral medicine
Respiratory medicine

Background:

Refractory chronic cough significantly impacts quality of life.
Limited effective and accessible treatment options exist for chronic cough.

Purpose of the Study:

To assess the efficacy of internet-based behavioral cough suppression therapy (IBCST).
To explore patient experiences with IBCST for refractory chronic cough.

Main Methods:

A 5-week randomized controlled trial compared IBCST with a healthy lifestyle control.
Participants completed the Leicester Cough Questionnaire (LCQ) and Cough Severity Visual Analog Scale (VAS).
Qualitative interviews explored user experiences with IBCST.

Main Results:

72% of IBCST participants showed clinically significant LCQ improvements at 1 week and 76% at 1 month.
While VAS scores trended positively, they did not reach statistical significance.
Qualitative data indicated high participant satisfaction with IBCST's convenience and effectiveness.

Conclusions:

IBCST is a feasible and efficacious treatment for refractory chronic cough.
IBCST demonstrates comparable efficacy to other behavioral cough suppression therapies.
Findings support the adaptation of IBCST into a digital therapeutic.