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Internet-Based Behavioral Cough Suppression Therapy for Refractory Chronic Cough: A Randomized Controlled Trial.
Jane R Salois1, Kassidi L Heinle1, Laurie J Slovarp1
1School of Speech, Language, Hearing, & Occupational Sciences, University of Montana, Missoula.
American Journal of Speech-Language Pathology
|August 14, 2025
Summary
Internet-based behavioral cough suppression therapy (IBCST) effectively reduced chronic cough symptoms in adults. Participants reported high satisfaction with the convenient, online treatment, showing significant improvements in quality of life.
Area of Science:
- Digital therapeutics
- Behavioral medicine
- Respiratory medicine
Background:
- Refractory chronic cough significantly impacts quality of life.
- Limited effective and accessible treatment options exist for chronic cough.
Purpose of the Study:
- To assess the efficacy of internet-based behavioral cough suppression therapy (IBCST).
- To explore patient experiences with IBCST for refractory chronic cough.
Main Methods:
- A 5-week randomized controlled trial compared IBCST with a healthy lifestyle control.
- Participants completed the Leicester Cough Questionnaire (LCQ) and Cough Severity Visual Analog Scale (VAS).
- Qualitative interviews explored user experiences with IBCST.
Main Results:
- 72% of IBCST participants showed clinically significant LCQ improvements at 1 week and 76% at 1 month.
- While VAS scores trended positively, they did not reach statistical significance.
- Qualitative data indicated high participant satisfaction with IBCST's convenience and effectiveness.
Conclusions:
- IBCST is a feasible and efficacious treatment for refractory chronic cough.
- IBCST demonstrates comparable efficacy to other behavioral cough suppression therapies.
- Findings support the adaptation of IBCST into a digital therapeutic.
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