Kidney failure risk equation (KFRE), A risk-based triage for nephrology referrals: A mixed-methods study at

Nur Raziana Rozi1, Christine Shamala Selvaraj2, Jia-Kai Tan3

  • 1Department of Medicine, Kulliyyah of Medicine, International Islamic University Malaysia (IIUM), Kuantan, Malaysia.

Primary Care Diabetes
|August 14, 2025
PubMed

Insights

Healthcare providers identified patient insight gaps and system shortfalls as key barriers to managing chronic kidney disease (CKD). Implementing the kidney failure risk equation (KFRE) may improve targeted nephrology referrals and patient outcomes.

Area of Science:

  • Nephrology
  • Public Health
  • Healthcare Management

Background:

  • Chronic kidney disease (CKD) is a global health concern with limited understanding of healthcare provider (HCP) perspectives on management.
  • Exploring facilitators and barriers to CKD management is crucial for improving patient care.
  • Integrating risk-based triage tools like the kidney failure risk equation (KFRE) can enhance referral processes.

Purpose of the Study:

  • To explore HCPs' perspectives on facilitators and barriers to CKD management.
  • To assess perceived benefits and challenges of implementing the KFRE for nephrology referrals.
  • To identify strategies for enhancing CKD care before KFRE implementation.

Main Methods:

  • Mixed methods approach combining semi-structured interviews and job satisfaction surveys.
  • Thematic analysis of transcribed interviews with 27 HCPs across primary care, nephrology, and endocrinology.
  • Quantitative survey data collected from 111 HCPs at Universiti Malaya Medical Centre.

Main Results:

  • Top barriers to CKD management include suboptimal patient insights, practice gaps, and healthcare system shortfalls.
  • Key facilitators include strong interdisciplinary networks and access to specialist resources.
  • HCPs perceived the KFRE as a potentially useful tool for targeted nephrology referrals.

Conclusions:

  • Addressing modifiable barriers and leveraging facilitators can improve CKD patient outcomes.
  • The KFRE shows promise for facilitating targeted nephrology referrals and optimizing resource allocation.
  • Enhanced interdisciplinary collaboration and patient education are vital for effective CKD management.
Abstract

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