Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood and Nerve Supply to the Bones01:29

Blood and Nerve Supply to the Bones

Bones are dynamic organs that require a rich supply of oxygen and nutrients. Around 5% to 10% of the cardiac output supplies blood to the bones. A typical long bone has three main sources: the nutrient artery, the metaphyseal and epiphyseal arteries, and the periosteal arteries.
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Early Sepsis Diagnosis as a Global Imperative: The Role of Raman Spectroscopy.

Journal of clinical medicine·2026
Same author

Graphene-Based 3D Scaffolds in Bone Regeneration: Emerging Opportunities for MRONJ Treatment.

Pharmaceutics·2026
Same author

Label-Free Imaging of Red Blood Cells in Gestational Diabetes: Autofluorescence Captures Oxidative Stress Beyond Membrane Fluidity.

Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada·2026
Same author

<i>FMR1</i> RNA interaction with DNMT1 blocks DNA methylation at the <i>FMR1 locus</i>.

NAR molecular medicine·2026
Same author

The Diabetic Nose: A Narrative Review of Rhinologic Involvement in Diabetes (1973-2025).

Journal of clinical medicine·2026
Same author

3D-Printed Multifunctional Multicompartment Polymer-Based Capsules for Tunable and Spatially Controlled Drug Release.

Journal of functional biomaterials·2025

Related Experiment Video

Updated: Jun 16, 2026

Temporomandibular Joint Pain Measurement by Bite Force and Von Frey Filament Assays in Mice
06:37

Temporomandibular Joint Pain Measurement by Bite Force and Von Frey Filament Assays in Mice

Published on: September 13, 2024

1.1K

Using Quantitative Masticatory Dysfunction to Inform Pain Management in Trigeminal Neuralgia Through

Alessia Riente1,2, Alessio Abeltino1,2, Cassandra Serantoni1,2

  • 1Metabolic Intelligence Lab, Department of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy.

Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
|August 15, 2025
PubMed
Summary

Trigeminal neuralgia (TN) patients exhibit distinct chewing patterns, including longer chewing times and reduced force, identified using the "Chewing" device. This may help in personalized treatment strategies for facial pain.

Keywords:
chewing behaviorclustering analysiselectromyographymasticatory dysfunctionpain managementtrigeminal neuralgia

More Related Videos

Assessment of Nerve Injury-Induced Mechanical Hypersensitivity in Rats Using an Orofacial Operant Pain Assay
07:39

Assessment of Nerve Injury-Induced Mechanical Hypersensitivity in Rats Using an Orofacial Operant Pain Assay

Published on: July 26, 2022

3.8K
Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain
09:35

Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain

Published on: May 10, 2017

19.0K

Related Experiment Videos

Last Updated: Jun 16, 2026

Temporomandibular Joint Pain Measurement by Bite Force and Von Frey Filament Assays in Mice
06:37

Temporomandibular Joint Pain Measurement by Bite Force and Von Frey Filament Assays in Mice

Published on: September 13, 2024

1.1K
Assessment of Nerve Injury-Induced Mechanical Hypersensitivity in Rats Using an Orofacial Operant Pain Assay
07:39

Assessment of Nerve Injury-Induced Mechanical Hypersensitivity in Rats Using an Orofacial Operant Pain Assay

Published on: July 26, 2022

3.8K
Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain
09:35

Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain

Published on: May 10, 2017

19.0K

Area of Science:

  • Neurology
  • Biomedical Engineering
  • Clinical Diagnostics

Background:

  • Trigeminal neuralgia (TN) is a rare neurological disorder causing severe facial pain, often misdiagnosed, affecting approximately 5 in 100,000 individuals annually.
  • The condition predominantly impacts women aged 50-70 and presents diagnostic challenges, leading to delayed treatment and prolonged suffering.

Purpose of the Study:

  • To evaluate masticatory dysfunction in individuals with and without Trigeminal Neuralgia (TN).
  • To assess the utility of an electromyographic device, "Chewing", in quantifying pain-related masticatory dysfunction.
  • To explore how these findings can inform personalized treatment approaches for TN.

Main Methods:

  • An observational study involving TN patients and healthy controls.
  • Utilized the "Chewing" electromyographic device to monitor masticatory behavior during consumption of apple and carrot.
  • Recorded parameters like chewing time, number of chews, and chewing force, followed by unsupervised learning for pattern clustering.

Main Results:

  • Two distinct masticatory behavior clusters were identified.
  • Cluster 1, comprising 27.5% of TN patients, showed significantly prolonged chewing time, increased chew counts, and reduced chewing force compared to Cluster 0.
  • TN patients were more prevalent in Cluster 1, indicating a correlation between altered masticatory patterns and trigeminal neuralgia.

Conclusions:

  • The "Chewing" device effectively quantified and differentiated masticatory patterns in TN patients.
  • Identifying subgroups based on masticatory behavior offers potential for tailored treatment strategies.
  • This approach may lead to improved patient outcomes in managing Trigeminal Neuralgia.