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Proteins are broken down into amino acids during digestion. Unlike fats and carbohydrates, which are stored for later use, proteins are not. Instead, amino acids are either used to produce ATP through oxidation or contribute to the creation of new proteins for the growth and repair of the body. Any surplus amino acids from the diet are converted into glucose or triglycerides rather than excreted.
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  11. Metabolic Profiling Of Bovine Colostrum: Unravelling The Influences Of Diet And Seasonality On Functional Dairy Components.
  1. Home
  3. Research Domains
  5. Agricultural, Veterinary And Food Sciences
  7. Food Sciences
  9. Food Nutritional Balance
  11. Metabolic Profiling Of Bovine Colostrum: Unravelling The Influences Of Diet And Seasonality On Functional Dairy Components.

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Metabolic profiling of bovine colostrum: unravelling the influences of diet and seasonality on functional dairy components.

Raghunath Pariyani1, Gabriele Rocchetti2, Aidan Lawless3

  • 1School of Food & Nutritional Sciences, University College Cork, Cork T12Y337, Ireland.

Food Chemistry
|August 15, 2025

View abstract on PubMed

Summary
This summary is machine-generated.

Seasonal changes significantly alter bovine colostrum

Keywords:
ColostrumCow dietDairy lipidsFunctional food

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Area of Science:

  • Nutritional science and metabolomics.
  • Animal science and food technology.

Background:

  • Bovine colostrum is recognized for its health benefits in functional foods.
  • Limited understanding exists regarding seasonal and dietary impacts on colostrum's bioactive metabolome.

Purpose of the Study:

  • To characterize the metabolic profile of bovine colostrum based on calving season.
  • To identify key metabolites influenced by seasonality, diet, and environmental factors.

Main Methods:

  • Utilized ultra-high-performance liquid chromatography-high-resolution mass spectrometry (UHPLC-HRMS).
  • Conducted untargeted metabolomic analysis on colostrum from cows calving in autumn and spring.

Main Results:

  • Demonstrated distinct seasonal variations in colostrum's metabolic profile.
Milk metabolomics
Seasonality
  • Identified 22 metabolites, including phospholipids, peptides, and nucleotides, significantly increased in autumn colostrum.
  • Glycyl aspartate and D-erythro-imidazole-glycerol-phosphate identified as key seasonal biomarkers.

    • Conclusions:

    • Seasonality profoundly impacts the bovine colostrum metabolome.
    • Pre-partum diet and temperature correlate with metabolic variations; parity and genetics have minor effects.
    • Findings offer insights for developing season-optimized, colostrum-based functional foods.