Related Experiment Video
Updated: Sep 11, 2025

Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease
Published on: January 20, 2010
Tracheobronchoplasty for Excessive Dynamic Airway Collapse and Tracheobronchomalacia: A Comparative Analysis of
Jae M Cho1, Paolo de Angelis1, Fleming Mathew1
1Division of Thoracic Surgery and Interventional Pulmonology, Department of Surgery, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Background:
Excessive dynamic airway collapse (EDAC) and tracheobronchomalacia (TBM) are distinct causes of excessive central airway collapse; EDAC is characterized by excessive anterior displacement of the posterior membrane, whereas TBM is due to weakness of the cartilaginous rings. We compared outcomes after tracheobronchoplasty across these 2 pathologic processes.
Methods:
This was a single-center retrospective study including patients who underwent tracheobronchoplasty between 2018 and 2023. Preoperative dynamic computed tomography scans were reviewed by 4 airway experts, and patients were assigned to 2 groups (EDAC and TBM) on the basis of consensus diagnosis.
Results:
The study included 73 consecutive patients who underwent tracheobronchoplasty with a consensus diagnosis of EDAC (n = 47) or TBM (n = 26). Patients with EDAC were less likely to have diabetes (15% vs 54%; P < .01) and more likely to undergo robotic tracheobronchoplasty (30% vs 4%; P = .01). There were no significant differences in rates of minor complications (60% vs 81%; P = .07), major complications (21% vs 35%; P = .17), or overall Clavien-Dindo scores (21 vs 21.75; P = .21). Intensive care unit and hospital length of stay, rates of 30-day readmissions, and home discharges were also similar. Both groups achieved clinically meaningful improvements in quality of life score and 6-minute walk test distance at the first follow-up.
Conclusions:
Differentiating EDAC and TBM is challenging for clinicians because of the overlapping clinical symptoms. Despite anatomic differences, surgical outcomes are comparable. This supports the role of tracheobronchoplasty as a definitive treatment of excessive central airway collapse, regardless of cause. Diagnostic differentiation remains important for mechanistic understanding but should not preclude surgical candidacy.
Related Concept Videos
Trachea
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of...
Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques
The Bronchial Tree
The trachea, commonly known as the windpipe, is a tube that connects the larynx (voice box) to the bronchi. At a point called the carina, it bifurcates into two primary bronchi. The right primary bronchus is wider, shorter, and more vertical than the left primary...
Tracheostomy Decannulation
Description of the Procedure
Decannulation refers to the permanent removal of the tracheostomy tube, signaling the resolution of the condition that initially necessitated the tracheostomy. The process requires a well-coordinated interplay between...
Tracheostomy: Procedure and Tubes
Tracheostomy tubes can be made of semiflexible plastic (polyurethane or silicone), rigid plastic, or metal, and they come in...
Oxygen Delivering System III: Tracheostomy and T-piece
Tracheostomy
A tracheostomy is a surgically created opening (stoma) in the anterior part of the trachea. It is used to establish a patient airway, bypass an upper airway obstruction, simplify the removal of secretions, permit long-term...

