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Relationship Between Bruxism and Depression: Systematic Literature Review and Meta-Analysis
The International Journal of Prosthodontics
|August 16, 2025
Summary
Individuals with bruxism, including sleep and awake types, have significantly higher odds of experiencing depression. This association remained consistent across various assessment methods and over time, underscoring the need for integrated care.
Area of Science:
- Psychiatry and Behavioral Sciences
- Dental Sleep Medicine
- Epidemiology
Background:
- Bruxism, encompassing sleep and awake types, is a prevalent condition often associated with psychological distress.
- Understanding the link between bruxism and depression is crucial for effective patient management.
- Previous research has yielded varied results, necessitating a comprehensive synthesis of evidence.
Purpose of the Study:
- To systematically review and meta-analyze the association between depression and different classifications of bruxism.
- To examine how assessment methods and bruxism types influence this association.
- To evaluate the temporal trends of this association from 2002 to 2025.
Main Methods:
- A systematic review and meta-analysis adhering to PRISMA guidelines.
- Inclusion of observational studies (cross-sectional, case-control, cohort) in young adults (18-59 years).
- Comprehensive search of PubMed/MEDLINE, Embase, and Brazilian Dentistry Oral Sciences databases.
Main Results:
- Forty-eight articles were included in the review; 26 in the meta-analysis.
- A significant positive association between all types of bruxism and depression was observed (OR=2.84).
- This association remained consistent across diagnostic methods and over time, except for electromyography in sleep bruxism diagnosis.
Conclusions:
- Depression assessment is vital in the multidisciplinary management of sleep and awake bruxism.
- Future studies should clearly differentiate and assess sleep and awake bruxism in relation to depression.
- The findings highlight the importance of considering psychological comorbidities in bruxism patients.
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