Longitudinal changes in delirium motor subtypes among patients with advanced cancer in inpatient hospice and palliative care units: A secondary analysis of a multicenter cohort study

  • 0Center for Psycho-Oncology and Palliative Care, Nagoya City University Hospital, Mizuho-Cho, Mizuho-Ku, Nagoya, 467-8601, Japan. takaaki_hase@bird.ocn.ne.jp.

Summary

This summary is machine-generated.

Delirium motor subtypes in palliative care are often stable, but some patients shift. Maintaining communication capacity without agitation is challenging for those with delirium.

Area Of Science

  • Geriatrics
  • Palliative Care
  • Neuroscience

Background

  • Delirium is common in palliative care.
  • Motor subtypes of delirium (hypoactive, hyperactive, mixed) may have different prognoses.
  • The stability of these subtypes during a palliative care unit stay is not well understood.

Purpose Of The Study

  • To examine the longitudinal changes in delirium motor subtypes among patients receiving palliative care.
  • To assess the stability of hypoactive versus hyperactive/mixed delirium subtypes.

Main Methods

  • Secondary analysis of a multicenter observational study of advanced cancer patients.
  • Delirium motor subtypes, agitation (MDAS item 9), and communication capacity (CCS item 4) were assessed.
  • Assessments occurred at admission (T0), before death (T1), and daily.

Main Results

  • Over 9,000 delirium assessments were analyzed from 1,633 patients.
  • 57% of patients remained in their initial delirium motor subtype (hypoactive or hyperactive/mixed) until death.
  • Patients with delirium at admission were less likely to maintain communication capacity without moderate-to-severe agitation at the end of life.

Conclusions

  • Delirium motor subtypes show considerable stability during palliative care.
  • Balancing patient comfort and communication capacity is a key challenge.
  • Individualized delirium management goals require discussion with caregivers.

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