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Updated: Sep 11, 2025

Author Spotlight: A Multi-Depth Porcine Model for Comprehensive Study of Burn Injuries and Healing Processes
Published on: February 23, 2024
Burn Care: A Review-Part 1: First 48 Hours
David G Greenhalgh1,2, Vinita Puri3
1Emeritus Chief of Burns, Shriners Children's Northern California, Sacramento, California, USA.
Background:
The purpose of part one of this review is to provide basic information about the initial treatment of all burns.
Methods:
The current literature and experience of the author were used to provide guidelines for treating burns in all parts of the world. No artificial intelligence was used to create this manuscript.
Results:
Although survival has improved, burns often lead to significant scarring and disabilities. While there are new and expensive technologic advances, basic burn care can be performed with relatively few resources. Early treatment can have a significant impact on outcomes. This review describes guidelines for worldwide use and introduces the newest technologies for treating burns. Because it is difficult to include all information in one paper, the review will be divided into two sections, the first section describing epidemiology, pathophysiology and the initial 48 h of treatment. The second part will cover care after 2 days.
Conclusion:
Any caregiver should be able to manage the first 48 h. The real challenge starts after 48 h when care, at least for large burns, can last years.
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