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Suppurative infections after lower third molar surgery: a systematic review
1Department of Odontostomatological and Maxillo Facial Sciences Via Caserta 6, 00161, Rome roberto.pippi@uniroma1.it.
Medicina Oral, Patologia Oral Y Cirugia Bucal
|August 16, 2025
Summary
Antibiotic prophylaxis significantly reduces purulent infections after lower third molar surgery. This finding is crucial for preventing complications and guiding evidence-based dental practices.
Area of Science:
- Oral Surgery
- Infectious Diseases
- Evidence-Based Dentistry
Background:
- Suppurative infections are a potential complication following lower third molar surgery.
- These infections can spread to adjacent tissues and deep fascial spaces.
Purpose of the Study:
- To systematically review the literature on post-operative purulent infections after lower third molar extraction.
- To identify risk factors, involved spaces, and therapies for these infections.
Main Methods:
- Systematic review adhering to 2020 PRISMA guidelines.
- Comprehensive literature search in Medline (via Pubmed) and SCOPUS databases.
- Statistical analysis using hypothesis tests for differences between means with unknown variances.
Main Results:
- Eleven articles were included, totaling 7363 extractions.
- The overall incidence of purulent infections was 5.35%.
- A significantly higher incidence of infections was observed in patients not receiving antibiotic prophylaxis.
Conclusions:
- There is limited scientific literature on post-operative purulent infections following lower third molar surgery.
- Antibiotic prophylaxis was identified as the sole variable significantly reducing the incidence of these infections.
- Further research is needed to establish evidence-based preventive and therapeutic strategies.
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