Related Experiment Video
Updated: Sep 11, 2025
07:27
Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance
Published on: August 25, 2021
2.0K
Revised Ocular Trauma Score (rOTS): to develop and internally validate a predictive model for visual outcomes after
Parinee Kemchoknatee1,2, Jayanton Patumanond3,4, Somporn Chantra2,5
1Division of Neuro-ophthalmology, Department of Ophthalmology, Rajavithi Hospital, Rangsit University, Bangkok, Thailand tsrisombut@gmail.com parinee.eye52@gmail.com.
BMJ Open Ophthalmology
|August 17, 2025
Summary
A new prognostic model predicts visual outcomes for open globe injury (OGI) patients. Initial visual acuity is the strongest predictor, aiding emergency assessments for better patient care.
Area of Science:
- Ophthalmology
- Trauma Surgery
- Medical Prognostics
Background:
- Open globe injury (OGI) poses a significant risk to visual function.
- Accurate prediction of visual outcomes is crucial for timely and effective management.
- Existing prognostic tools may require refinement for diverse patient populations.
Purpose of the Study:
- To develop and validate a prognostic scoring model for predicting poor visual outcomes (≤20/200) in patients with OGI.
- To identify key predictors of visual acuity at 6 months post-injury.
- To create risk stratification categories (mild, moderate, severe) for OGI patients.
Main Methods:
- Retrospective cohort study involving 311 OGI patients from two Thai teaching hospitals (2016-2023).
- Development of a multivariable logistic regression model to predict final visual acuity at 6 months.
- Model performance assessed using ROC analysis and internal validation via bootstrapping (500 replications).
Main Results:
- 42.77% of patients experienced visual acuity worse than 20/200 at 6 months.
- Initial visual acuity, relative afferent pupillary defect, rupture, and eyelid injury were significant predictors.
- The model demonstrated satisfactory discrimination (C-statistic=0.8671) and calibration, with risk groups showing significant differences in poor visual outcomes (Moderate OR=1.51, Severe OR=45.06).
Conclusions:
- The revised Ocular Trauma Score is a valuable tool for predicting visual outcomes in OGI patients in emergency settings.
- Presenting visual acuity is the most critical factor in predicting prognosis.
- Further external validation is recommended due to study limitations, including a predominance of severe cases and lack of pediatric data.
