Tobacco and other substance co-use among adolescents and young adults with cancer who use tobacco: prevalence and associations with nicotine dependence and depression
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View abstract on PubMed
Summary
This summary is machine-generated.Adolescent and young adult cancer survivors show high rates of substance co-use, similar to their peers. Alcohol co-use was linked to lower nicotine dependence in survivors with major depression.
Area Of Science
- Oncology
- Public Health
- Substance Use Research
Background
- Substance co-use, including tobacco, cannabis, and alcohol, is prevalent among adolescents and young adults (AYAs).
- Limited research exists on substance co-use patterns in AYA cancer survivors.
- Understanding these patterns is crucial for survivorship care and long-term health.
Purpose Of The Study
- To compare past-month substance co-use prevalence between AYAs with and without cancer history.
- To examine associations between substance co-use and nicotine dependence in AYA cancer survivors who use tobacco.
- To investigate the moderating role of major depression in the relationship between co-use and nicotine dependence.
Main Methods
- Analysis of 2015-2019 National Survey on Drug Use and Health data.
- Inclusion of 7793 AYAs (228 with cancer history, 7565 without).
- Use of weighted logistic regression models to assess associations and moderation by major depression.
Main Results
- AYA cancer survivors reported lower past-month cannabis co-use (29% vs 39%), but this was not significant in multivariable analysis.
- Among AYA cancer survivors using tobacco, alcohol co-use was associated with lower nicotine dependence when major depression was present (aOR=0.08).
Conclusions
- Substance co-use rates are high and consistent across cancer history among AYAs who use tobacco.
- Alcohol co-use may decrease nicotine dependence in tobacco-using AYA cancer survivors with major depression, contrary to previous research.
- Further research is needed on nuanced substance use patterns and motivations for behavior change in this population.
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