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Updated: Sep 11, 2025

Light-driven Enzymatic Decarboxylation
Published on: May 22, 2016
Enhancing Photocatalytic Decarboxylation by Frustrated Lewis Acid-Base Pairs for Efficient Degradation of
Wenhui Ding1,2, Tianhao Tang1, Xianjun Tan1
1Institute of Environment and Ecology, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, P. R. China.
Abstract:
Recognized as a "forever chemical", perfluorooctanoic acid (PFOA) calls for urgent environmental cleanup. Photocatalytic degradation emerged as a sustainable solution, but it still suffers from sluggish reaction kinetics and insufficient C-F bond cleavage. Addressing the above bottlenecks, we strategically constructed frustrated Lewis acid-base pairs (FLP) on In2O3 photocatalyst, which theoretically reduces the PFOA decarboxylation energy by 2.91 eV. The rationally designed In2O3-FLP photocatalyst achieved a 23-fold improvement of PFOA degradation rate, a 9-fold increase of defluorination rate, and a 1.6-fold increase of mineralization efficiency compared to pristine In2O3. Mechanistic studies reveal that the frustrated Lewis acid (LA) and Lewis base (LB) synergistically facilitate PFOA degradation by enhancing adsorption, promoting charge transfer, and enabling in situ defluorination. This work elucidates mechanistic insights into dual-active-site catalysis via FLP in photocatalytic decarboxylation and proposes a rational photocatalyst design strategy for persistent pollutant remediation.
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