[Microcirculation and permeability of the blood-carrying capillaries in chronic hepatitis patients]

Microcirculation and transcapillary exchange were studied in 40 patients with chronic persistent hepatitis and in 32 patients with chronic active hepatitis (15 patients with a slow progressive course and 17 patients with a rapidly progressive course) using methods of conjunctive biomicroscopy, isotope intracutaneous capillarography and V. P. Kaznacheev's capillaro-venous method with a hydrostatic load. Significant disorders of the microcirculation (extravascular, vascular and intravascular) and pronounced disorders of transcapillary exchange resulting in the development of the syndrome of capillarotrophic insufficiency were revealed in the patients with chronic hepatitis. The degree of microcirculatory and transcapillary exchange changes was in direct relation to the activity of liver pathology.