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Structural Studies of Macromolecules in Solution using Small Angle X-Ray Scattering
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Snapshot of an intermediate structure

Akira Shinohara1,2

  • 1Institute for Protein Research, The University of Osaka, Osaka, Japan.

Elife
|August 18, 2025
PubMed

Abstract:

Cryogenic electron microscopy has been used to determine the detailed structure of an intermediate state called a "D-loop" that forms when strands of DNA are exchanged during homologous recombination.

Keywords:
D-loopDNA repairRAD51chromosomesgene expressionhomologous recombinationhomology searchhumanmolecular biophysicsstrand exchangestructural biology

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