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Moxifloxacin-Induced Seizures: A Case Report.
Joana Cartucho1, Bruno Bonito1, Bruna Rodrigues Barbosa1
1Internal Medicine, Unidade Local de Saúde do Arco Ribeirinho, Barreiro, PRT.
Cureus
|August 18, 2025
Summary
Fluoroquinolone antibiotics like moxifloxacin can cause seizures by affecting brain chemicals. This risk is higher with prolonged use or in patients taking multiple medications, even without organ damage.
Area of Science:
- Neuropharmacology
- Clinical Neurology
- Infectious Diseases
Background:
- Fluoroquinolones are broad-spectrum antibiotics with favorable pharmacokinetics.
- Concerns exist regarding fluoroquinolone neurotoxicity, especially in vulnerable individuals.
- Moxifloxacin is a commonly prescribed fluoroquinolone antibiotic.
Keywords:
adverse drug reactiondrug-induced seizuresfluoroquinolones neurotoxicitygaba-a antagonismmoxifloxacinnmda stimulationMore Related Videos
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