Optimizing Cardiovascular Care in Aging Populations: A Comprehensive Review of Geriatric Cardiology

Shreya Agarwal1, Ifeoma N Ozor2, Siri Chithanuru3

  • 1Internal Medicine, JSS Medical College, Mysore, IND.

Cureus
|August 18, 2025
PubMed

Insights

Integrated, evidence-based care models improve cardiovascular health in older adults. These strategies address frailty, multimorbidity, and polypharmacy, enhancing functional independence and quality of life.

Area of Science:

  • Geriatric Cardiology
  • Cardiovascular Disease in Older Adults
  • Integrative Healthcare Models

Background:

  • Cardiovascular diseases (CVDs) are a major health concern in the aging population.
  • Older adults often present with geriatric syndromes like multimorbidity, frailty, and polypharmacy, complicating standard care.
  • Traditional disease-focused models are insufficient for comprehensive geriatric cardiovascular care.

Purpose of the Study:

  • To explore the efficacy of integrated, evidence-based multidisciplinary cardiovascular care models in geriatric adults.
  • To evaluate and compare the impact of these models versus traditional practices.
  • To identify key challenges and recent innovations in cardiovascular care for aging populations.

Main Methods:

  • A narrative review of recent literature from databases such as Cochrane and PubMed.
  • Keywords included "older adults", "cardiovascular disease", "frailty", and "polypharmacy".
  • Thematic synthesis was used to analyze findings from cohort studies, scientific statements, systematic reviews, meta-analyses, and narrative reviews published within the last 15 years.

Main Results:

  • Integrated, multidisciplinary, and patient-centered strategies are essential for improving health outcomes and functional independence in older adults with CVD.
  • Key challenges in geriatric cardiology include managing multimorbidity, cognitive impairment, and polypharmacy.
  • Evidence-based updates and practical approaches are needed to address diagnostic and therapeutic complexities.

Conclusions:

  • Integrated cardiovascular care models show promise for improving clinical outcomes and quality of life in geriatric populations.
  • Addressing health inequities and disparities is crucial in cardiogeriatric care.
  • Future research and policy development are needed to optimize cardiovascular care for aging individuals.

Related Concept Videos

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are not...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism

Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...