Long-term survival after multidisciplinary heart team-guided management of complex coronary artery disease

Taylor Pickering1, Austin Kluis1,2, Emily Shih1,2

  • 1Baylor Scott & White Research Institute, Plano, Texas, USA.

Proceedings (Baylor University. Medical Center)
|August 18, 2025
PubMed

Insights

A multidisciplinary heart team approach for complex coronary artery disease (CAD) showed high adherence to recommendations (92%) and improved patient outcomes. Coronary artery bypass grafting (CABG) demonstrated the lowest mortality rates.

Area of Science:

  • Cardiology
  • Clinical Medicine
  • Health Services Research

Background:

  • Guidelines advocate for a multidisciplinary heart team in complex coronary artery disease (CAD) management.
  • However, data on the impact of this approach on clinical outcomes and adherence is limited.

Purpose of the Study:

  • To evaluate the adherence to heart team recommendations and clinical outcomes in high-risk patients with complex CAD.
  • To assess the effectiveness of a multidisciplinary heart team approach in managing complex coronary artery disease.

Main Methods:

  • A prospective study involving 210 high-risk patients with complex CAD evaluated by a heart team.
  • Assessment of adherence to recommendations for coronary artery bypass grafting (CABG), percutaneous coronary intervention (PCI), hybrid PCI/CABG, or optimal medical therapy (OMT).
  • Clinical outcomes, including 30-day, 1-year, and 2-year mortality, were tracked.

Main Results:

  • High overall adherence to heart team recommendations (92%), with specific rates for CABG (96%), PCI (90%), OMT (87%), and hybrid PCI/CABG (75%).
  • Coronary artery bypass grafting (CABG) was the most recommended treatment (53%) and showed the lowest 1-year (4%) and 2-year (6%) mortality.
  • Percutaneous coronary intervention (PCI) was associated with significantly higher mortality (1-year: 28%, 2-year: 40%) compared to CABG and OMT.

Conclusions:

  • A single-center multidisciplinary heart team approach for complex CAD achieved high adherence and favorable outcomes.
  • This patient-centered model supports the integration of multidisciplinary evaluation into standard practice for high-risk CAD patients.
Abstract

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