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Updated: Sep 11, 2025

Author Spotlight: Enhancing Coronary Artery Revascularization
Published on: September 15, 2023
Long-term survival after multidisciplinary heart team-guided management of complex coronary artery disease
Taylor Pickering1, Austin Kluis1,2, Emily Shih1,2
1Baylor Scott & White Research Institute, Plano, Texas, USA.
Insights
A multidisciplinary heart team approach for complex coronary artery disease (CAD) showed high adherence to recommendations (92%) and improved patient outcomes. Coronary artery bypass grafting (CABG) demonstrated the lowest mortality rates.
Area of Science:
- Cardiology
- Clinical Medicine
- Health Services Research
Background:
- Guidelines advocate for a multidisciplinary heart team in complex coronary artery disease (CAD) management.
- However, data on the impact of this approach on clinical outcomes and adherence is limited.
Purpose of the Study:
- To evaluate the adherence to heart team recommendations and clinical outcomes in high-risk patients with complex CAD.
- To assess the effectiveness of a multidisciplinary heart team approach in managing complex coronary artery disease.
Main Methods:
- A prospective study involving 210 high-risk patients with complex CAD evaluated by a heart team.
- Assessment of adherence to recommendations for coronary artery bypass grafting (CABG), percutaneous coronary intervention (PCI), hybrid PCI/CABG, or optimal medical therapy (OMT).
- Clinical outcomes, including 30-day, 1-year, and 2-year mortality, were tracked.
Main Results:
- High overall adherence to heart team recommendations (92%), with specific rates for CABG (96%), PCI (90%), OMT (87%), and hybrid PCI/CABG (75%).
- Coronary artery bypass grafting (CABG) was the most recommended treatment (53%) and showed the lowest 1-year (4%) and 2-year (6%) mortality.
- Percutaneous coronary intervention (PCI) was associated with significantly higher mortality (1-year: 28%, 2-year: 40%) compared to CABG and OMT.
Conclusions:
- A single-center multidisciplinary heart team approach for complex CAD achieved high adherence and favorable outcomes.
- This patient-centered model supports the integration of multidisciplinary evaluation into standard practice for high-risk CAD patients.
Objective:
Guidelines recommend a multidisciplinary heart team approach for managing complex coronary artery disease (CAD), yet its impact on clinical outcomes and adherence to recommendations is rarely reported.
Methods:
Between June 2021 and August 2022, 210 high-risk patients with isolated, complex CAD were evaluated at our institution's weekly heart team conference for consideration of coronary artery bypass grafting (CABG), percutaneous coronary intervention (PCI), hybrid PCI/CABG, or optimal medical therapy (OMT). Adherence to recommendations and clinical outcomes, including 30-day, 1-year, and 2-year mortality, were assessed.
Results:
Overall adherence to heart team recommendations was 92%, with 96% adherence for CABG, 90% for PCI, 87% for OMT, and 75% for hybrid PCI/CABG. CABG was the most frequently recommended treatment (53%) and demonstrated the lowest mortality at 1 year (4%) and 2 years (6%) compared with PCI (1 year, 28%; 2 year, 40%) and OMT (1 year, 10%; 2 year, 20%). CABG patients had a lower-than-expected mortality (observed-to-expected ratio 0.9), while PCI was associated with significantly higher mortality (observed-to-expected ratio 3.0).
Conclusion:
This single-center multidisciplinary heart team approach for complex CAD offers a collaborative, patient-centered model that facilitates high adherence rates and favorable patient outcomes. These findings highlight the potential benefits of integrating multidisciplinary evaluation and support its implementation into standard practice for high-risk CAD patients.
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