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Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

26
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
26
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

20
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
20
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

25
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
25
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

27
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
27
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

204
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
204
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

17
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
17

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Related Experiment Video

Updated: Sep 11, 2025

Isolation and Characterization of Cardiac Mesenchymal Stromal Cells from Endomyocardial Bioptic Samples of Arrhythmogenic Cardiomyopathy Patients
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Tuberculous endocarditis: a case-based proposal for new diagnostic criteria.

M Higa1,2, H Munakata3, T Yamazato4

  • 1Dept. of Respiratory Medicine, Okinawa Prefectural Nanbu Medical Center & Children's Medical Center, Haebaru, Japan.

IJTLD Open
|August 18, 2025
PubMed
Summary

Tuberculous endocarditis (TBE) is a rare condition. This study proposes new diagnostic criteria for TBE, combining clinical, microbiological, and imaging findings to improve early recognition and management of this fatal disease.

Keywords:
Bentall procedureTBEcase reportgram staining of Mycobacterium tuberculosis

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Area of Science:

  • Infectious Diseases
  • Cardiology
  • Pathology

Background:

  • Tuberculous endocarditis (TBE) is a rare but severe manifestation of Mycobacterium tuberculosis.
  • Current diagnostic criteria for TBE are not standardized, hindering timely diagnosis and treatment.
  • Advanced diagnostic techniques are available, but their application in TBE requires clearer guidelines.

Purpose of the Study:

  • To present a case of TBE in a patient with a history of Bentall procedure.
  • To develop systematic diagnostic criteria for TBE based on a case report and literature review.
  • To improve the recognition and management of tuberculous endocarditis.

Main Methods:

  • A case of a 79-year-old male with suspected TBE was investigated.
  • Diagnostic methods included advanced imaging, histopathology, PCR, and microbial culture.
  • A comprehensive literature review was conducted to establish diagnostic criteria.

Main Results:

  • TBE was confirmed through histopathology and molecular identification of Mycobacterium tuberculosis.
  • New diagnostic criteria were proposed, categorized as 'Definitive', 'Probable', and 'Possible'.
  • The patient received surgical intervention and antimicrobial therapy, with outcomes aligned with improved strategies.

Conclusions:

  • TBE should be considered in infective endocarditis cases, particularly those with unusual presentations.
  • The proposed diagnostic criteria aim to enhance TBE recognition and guide clinical management.
  • A multidisciplinary approach is crucial for optimizing patient outcomes in TBE cases.