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Choline in immunity: a key regulator of immune cell activation and function

Catarina Maia1, Chin Wai Fung1, Elsa Sanchez-Lopez1

  • 1Department of Orthopedic Surgery, School of Medicine, University of California, San Diego, San Diego, CA, United States.

Frontiers in Immunology
|August 18, 2025
PubMed
Summary

Choline, a vital nutrient, is crucial for immune cell function, impacting cell membranes and gene expression. Research highlights its overlooked role in immunity and potential as a therapeutic target.

Keywords:
acetylcholine (ACh)cholinecholine kinase (ChoK)immune cellsimmunityinflammationphosphatidylcholine (PC)phosphocholine

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