Multiple myeloma with an unusual presentation

Central nervous system (CNS) involvement in multiple myeloma (MM) is rare and can be a challenge to diagnose due to the heterogenous symptoms and associated confounding neurological symptoms because of any other underlying condition. CNS - MM can occur either at the onset of the disease or during relapse when the myeloma is usually more aggressive and the patient would have already taken different types of treatments. CNS - MM has a grim prognosis inspite of the availability of newer modalities of pharmacologic treatment including immunomodulatory drugs and proteasome inhibitors. Here, we report a case of MM with CNS involvement at presentation which posed a diagnostic challenge. This case is being reported due to its rarity of occurrence and limited data available in literature.