Coronary Artery Anomalies in Review: Anomalous Origin, Aneurysms, and Fistulae

Jack A Hoover1,2, Keshika Catakam3, Rachel E Wittenberg3

  • 1Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

Insights

Coronary artery anomalies are rare congenital heart defects. This review covers their varied presentations, imaging, and individualized management strategies for better clinical decisions.

Area of Science:

  • Cardiology
  • Congenital Heart Disease
  • Vascular Anomalies

Background:

  • Coronary artery anomalies (CAAs) are uncommon congenital heart conditions with diverse origins and development.
  • Clinical presentations vary widely, from sudden cardiac arrest in athletes to asymptomatic incidental findings.

Purpose of the Study:

  • To provide an overview of coronary artery anomalies.
  • To discuss recent advancements in imaging, surgical planning, and risk stratification for CAAs.
  • To highlight challenges in optimizing management and achieving consensus.

Main Methods:

  • Literature review of coronary artery anomalies.
  • Analysis of recent advances in diagnostic imaging modalities.
  • Evaluation of current surgical planning and risk stratification approaches.

Main Results:

  • CAAs present a broad anatomical spectrum with significant clinical variability.
  • Individualized management is crucial, based on presentation, anatomy, and patient factors.
  • Gaps in evidence and consensus hinder optimal risk stratification and decision-making.

Conclusions:

  • Effective management of CAAs requires a personalized approach.
  • Further research is needed to refine risk stratification tools and clinical decision support.
  • Optimizing management strategies for CAAs remains an ongoing challenge.

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