Coronary Artery Anomalies in Review: Anomalous Origin, Aneurysms, and Fistulae
Jack A Hoover1,2, Keshika Catakam3, Rachel E Wittenberg3
1Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Insights
Coronary artery anomalies are rare congenital heart defects. This review covers their varied presentations, imaging, and individualized management strategies for better clinical decisions.
Area of Science:
- Cardiology
- Congenital Heart Disease
- Vascular Anomalies
Background:
- Coronary artery anomalies (CAAs) are uncommon congenital heart conditions with diverse origins and development.
- Clinical presentations vary widely, from sudden cardiac arrest in athletes to asymptomatic incidental findings.
Purpose of the Study:
- To provide an overview of coronary artery anomalies.
- To discuss recent advancements in imaging, surgical planning, and risk stratification for CAAs.
- To highlight challenges in optimizing management and achieving consensus.
Main Methods:
- Literature review of coronary artery anomalies.
- Analysis of recent advances in diagnostic imaging modalities.
- Evaluation of current surgical planning and risk stratification approaches.
Main Results:
- CAAs present a broad anatomical spectrum with significant clinical variability.
- Individualized management is crucial, based on presentation, anatomy, and patient factors.
- Gaps in evidence and consensus hinder optimal risk stratification and decision-making.
Conclusions:
- Effective management of CAAs requires a personalized approach.
- Further research is needed to refine risk stratification tools and clinical decision support.
- Optimizing management strategies for CAAs remains an ongoing challenge.
Abstract:
Coronary artery anomalies are rare congenital abnormalities involving abnormal coronary artery origin and incomplete/abnormal vessel development. These anomalies encompass a broad anatomical spectrum with varied clinical presentations ranging from sudden cardiac arrest in young athletes to incidental findings in asymptomatic adults. While more data on anatomy and clinical presentation has emerged in the last decade, management remains highly individualized, guided by clinical presentation, anatomical characteristics, and patient preferences. This review provides an overview of each anomaly and recent advances in imaging, surgical planning, and risk stratification. We also highlight the challenges in optimizing management strategies, addressing gaps in evidence, and achieving consensus to refine risk stratification tools and support clinical decision-making.
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