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Updated: Sep 11, 2025

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Intravascular Ultrasound Imaging-Guided Percutaneous Coronary Intervention: Evidence and Practical Implications
Safi U Khan1, Neal S Kleiman1, Alpesh R Shah1
1Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist, Houston, Texas, US.
Abstract:
Intravascular ultrasound (IVUS) has significantly advanced the field of percutaneous coronary intervention (PCI), offering enhanced visualization and assessment capabilities that surpass traditional angiography. IVUS technology generates images from reflected ultrasound waves, providing critical insights into plaque characteristics, vessel size, and lesion morphology. These capabilities facilitate precise stent placement, optimal sizing, and the identification of features associated with stent failure, such as underexpansion and malapposition. Studies have demonstrated that IVUS-guided PCI significantly reduces major adverse cardiovascular events and improves long-term outcomes, particularly in complex lesions. This comprehensive review outlines the technical nuances, evidence, and clinical applications of IVUS.
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