Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

CNS Stimulants: Cocaine, Amphetamines and Cannabinoids01:24

CNS Stimulants: Cocaine, Amphetamines and Cannabinoids

326
CNS stimulants, such as cocaine, amphetamines, and cannabinoids, have varying structures and mechanisms of action that lead to different therapeutic effects and side effects. Cocaine, with its molecular formula C17H21NO4, is a tropane alkaloid and a tertiary amino compound. It has two chemical forms: the hydrochloride salt and the "freebase." The former is in powder form, while the latter involves removing the hydrochloride salt to create a form that can be smoked. Cocaine exerts its...
326
Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

655
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
655
Stimulants01:29

Stimulants

312
Stimulants are substances that enhance neural activity and elevate dopamine levels in the brain, leading to their highly addictive nature. These drugs include cocaine, amphetamines, MDMA, caffeine, and nicotine, each with distinct mechanisms of action and varied health implications.
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
312
Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

289
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
289
Adrenergic Agonists: Mixed-Action Agents01:28

Adrenergic Agonists: Mixed-Action Agents

869
Mixed-action adrenergic agonists, like ephedrine and pseudoephedrine, directly and indirectly affect adrenergic receptors. These agents stimulate adrenoceptors and indirectly release stored neurotransmitters, amplifying the adrenergic response.
Ephedrine and pseudoephedrine lack a catecholamine group, making them less susceptible to degradation by metabolic enzymes. They have increased oral bioavailability and lipophilicity, resulting in a longer duration of action. Their response is reduced by...
869
Drugs Acting on Autonomic Ganglia: Stimulants01:23

Drugs Acting on Autonomic Ganglia: Stimulants

1.5K

Ganglionic stimulants activate NM nicotinic receptors in autonomic ganglia, falling into two categories: nicotine mimetics [e.g., lobeline, dimethylpiperazine, tetramethylammonium] and muscarinic receptor agonists [e.g., muscarine, methacholine]. The first category's action is rapid and blocked by nicotinic receptor antagonists, while the second category's action is delayed and blocked by atropine-like agents. Nicotine, an alkaloid, affects the heart rate by stimulating...
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Veil of Ignorance.

Palliative & supportive care·2026
Same author

Otherwise: A Discussion of Jane Kenyon and Her Place in the Medical Humanities.

Methodist DeBakey cardiovascular journal·2026
Same author

Falling Into Life: a Reflection on "Back" by Jane Kenyon.

Journal of general internal medicine·2026
Same author

Commentary on "Monet Refuses the Operation".

Academic medicine : journal of the Association of American Medical Colleges·2026
Same author

Heart Transplantation: Webcast June 5 2025.

Methodist DeBakey cardiovascular journal·2025
Same author

His Scream.

Journal of general internal medicine·2025
Same journal

Embolization Followed by Self-Repositioning of a CardioMEMS™ Wireless Pulmonary Artery Hemodynamic Monitoring Sensor Device.

Methodist DeBakey cardiovascular journal·2026
Same journal

Anomalous Origin of the Vertebral Artery from Thyrocervical Trunk: A Rare Anatomical Variant.

Methodist DeBakey cardiovascular journal·2026
Same journal

Intra-atrial Baffling of an Infradiaphragmatic Scimitar Vein without Circulatory Arrest.

Methodist DeBakey cardiovascular journal·2026
Same journal

Value of Myocardial Strain in Assessing Cardiac Masses: A Case Report.

Methodist DeBakey cardiovascular journal·2026
Same journal

Transient Cortical Blindness and Hemi-Spatial Neglect Following Watchman Device Implantation.

Methodist DeBakey cardiovascular journal·2026
Same journal

Hemodynamics of Pericardial Constriction: Role of Echocardiography and Cardiac Catheterization.

Methodist DeBakey cardiovascular journal·2026
See all related articles

Related Experiment Video

Updated: Sep 11, 2025

A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration
09:16

A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration

Published on: January 22, 2016

15.3K

Methamphetamine's Devastating Scourge.

Samra Iqbal1, Justin C Cordova2, James B Young3,4

  • 1PGY-2 Internal Medicine Resident, Texas Tech University Health Sciences Center, Amarillo, Texas, US.

Methodist Debakey Cardiovascular Journal
|August 18, 2025
PubMed
Summary
This summary is machine-generated.

Methamphetamine use is increasing, leading to a rise in methamphetamine-induced cardiomyopathy, a serious heart condition. This poem highlights the urgent need for medical awareness and action regarding this devastating health crisis.

Keywords:
methamphetaminemethamphetamine-induced cardiomyopathy

More Related Videos

Single Cell Measurement of Dopamine Release with Simultaneous Voltage-clamp and Amperometry
07:30

Single Cell Measurement of Dopamine Release with Simultaneous Voltage-clamp and Amperometry

Published on: November 21, 2012

13.9K
Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones
06:06

Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones

Published on: February 5, 2018

25.2K

Related Experiment Videos

Last Updated: Sep 11, 2025

A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration
09:16

A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration

Published on: January 22, 2016

15.3K
Single Cell Measurement of Dopamine Release with Simultaneous Voltage-clamp and Amperometry
07:30

Single Cell Measurement of Dopamine Release with Simultaneous Voltage-clamp and Amperometry

Published on: November 21, 2012

13.9K
Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones
06:06

Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones

Published on: February 5, 2018

25.2K

Area of Science:

  • Cardiology
  • Toxicology
  • Public Health

Background:

  • Methamphetamine use is increasing nationally.
  • Methamphetamine-induced cardiomyopathy is a rare but catastrophic complication.
  • This condition disproportionately affects young adults.

Purpose of the Study:

  • To raise awareness of methamphetamine-induced cardiomyopathy.
  • To highlight the utility of poetry in medical communication.
  • To call for increased medical community vigilance and action.

Main Methods:

  • Poetry as a medium for medical communication.
  • Case study reflection on methamphetamine-induced cardiomyopathy.
  • Analysis of substance abuse trends and their health impacts.

Main Results:

  • Poetry can effectively alert medical professionals to emerging health crises.
  • Methamphetamine-induced cardiomyopathy presents significant diagnostic and treatment challenges.
  • The condition has devastating and often permanent consequences, particularly for young adults.

Conclusions:

  • Increased awareness and early diagnosis of methamphetamine-induced cardiomyopathy are critical.
  • Medical professionals must be vigilant for this condition in young adults.
  • Poetry can serve as a unique tool to communicate urgent public health issues.