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Correlation between endo-perio lesions and systemic diseases: A cross-sectional study
Rahul Singh1, Nidhi Singh2, Simran Chauhan3
1Department of Conservative Dentistry and Endodontics, Sarjug Dental College and Hospital, Darbanga, India.
Bioinformation
|August 18, 2025
Summary
Systemic diseases are strongly linked to the severity of endodontic-periodontal lesions. This association is particularly pronounced in older males, highlighting a significant correlation.
Area of Science:
- Oral medicine
- Periodontology
- Endodontics
Background:
- Endodontic-periodontal lesions represent complex pathologies affecting tooth-supporting structures.
- Systemic diseases are increasingly recognized as influencing oral health outcomes.
- Understanding the interplay between systemic health and these lesions is crucial for comprehensive patient care.
Purpose of the Study:
- To investigate the correlation between endodontic-periodontal lesions and systemic diseases.
- To analyze the association of these lesions with age and gender distribution.
Main Methods:
- A cohort of 800 participants (aged 25-75 years) was evaluated.
- Participants were classified based on the presence or absence of systemic diseases (e.g., diabetes, hypertension, cardiovascular disorders, arthritis, kidney/liver dysfunction).
- Clinical and radiographic assessments were used to categorize lesions as primary endodontic, primary periodontal, or true combined.
Main Results:
- A significant correlation was found between the presence of systemic diseases and the severity of endodontic-periodontal lesions.
- Older males exhibited a particularly strong association between systemic diseases and lesion severity.
- Age and gender were identified as important factors in the manifestation and severity of these combined lesions.
Conclusions:
- Systemic diseases are strongly correlated with the severity of endodontic-periodontal lesions.
- The findings suggest that systemic health status significantly impacts the progression of these oral conditions.
- Healthcare providers should consider systemic health when managing patients with endodontic-periodontal lesions, especially older males.
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