Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Hyperbaric oxygen therapy for radiation myelitis.

T J Poulton, R L Witcofski

Undersea Biomedical Research

|December 1, 1985

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Organic solvents and exacerbation of M.S.

Aviation, space, and environmental medicine·1997

Same author

Retinal hemorrhage as a consequence of epidural steroid injection.

Archives of ophthalmology (Chicago, Ill. : 1960)·1996

Same author

When does a guideline become a standard?

Annals of emergency medicine·1994

Same author

Physiologic chest sounds and helicopter engine noise.

Aviation, space, and environmental medicine·1994

Same author

Fetal monitoring during air medical transport.

The Journal of air medical transport·1992

Same author

Visualization of coronary artery anastomoses by gas jet.

The Annals of thoracic surgery·1992

Same journal

Saturation decompression schedules based on a critical tissue supersaturation criterion.

Undersea biomedical research·1992

Same journal

The Americans with Disabilities Act and the injured diver.

Undersea biomedical research·1992

Same journal

Description and evaluation of a simple method for microbiological studies on otitis externa.

Undersea biomedical research·1992

Same journal

Posterior shoulder dislocation and humeral head necrosis in a recreational scuba diver with diabetes.

Undersea biomedical research·1992

Same journal

Pneumothorax as a complication of recompression therapy for cerebral arterial gas embolism.

Undersea biomedical research·1992

Same journal

Physiologically and subjectively acceptable breathing resistance in divers' breathing gear.

Undersea biomedical research·1992

See all related articles

Hyperbaric oxygen therapy (HBO) did not show benefits for radiation-induced myelitis in rats. This pilot study found no significant improvement in neurological function after HBO treatment for spinal cord damage.

Area of Science:

Radiation oncology
Hyperbaric medicine
Neurology

Background:

Radiation therapy can damage healthy tissues near tumors.
Hyperbaric oxygen therapy (HBO) is used for soft tissue and osteoradionecrosis.
HBO is considered for radiation-induced myelitis.

Purpose of the Study:

To evaluate the efficacy of HBO in treating radiation-induced myelitis in a rat model.
To determine if HBO provides clinical benefits for spinal cord damage caused by radiation.

Main Methods:

Radiation was used to induce myelitis in rat spinal cords.
Rats were randomized into HBO treatment and control groups 8 weeks post-irradiation.
Serial neurologic examinations were performed to assess outcomes.

Related Experiment Videos

Main Results:

No significant benefit or harm was observed in the HBO treatment group compared to the control group.
Neurologic examinations did not reveal clinically significant differences between the groups.

Conclusions:

This pilot study suggests HBO therapy does not offer a clinically significant benefit for radiation-induced myelitis in rats.
Further research may be needed to explore potential roles or alternative applications of HBO in radiation-related injuries.