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Development and validation of a pediatric pharmacological readiness assessment scale for recurrent respiratory

Yan Tang1, Qin Xu1, Ping Zhang1

  • 1The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Pakistan Journal of Pharmaceutical Sciences
|August 18, 2025
PubMed

Insights

A new scale assesses caregiver readiness for managing children's recurrent respiratory infections. This tool helps pharmacists improve medication adherence and reduce hospital readmissions.

Area of Science:

  • Pediatric pharmacology
  • Health services research
  • Patient adherence

Background:

  • Recurrent respiratory infections pose challenges in pediatric care.
  • Optimizing medication adherence and caregiver preparedness is crucial for managing these conditions.
  • Pharmacist-led interventions can significantly impact patient outcomes.

Purpose of the Study:

  • To develop and validate a Pediatric Pharmacological Readiness Assessment Scale (PPRAS).
  • To evaluate caregiver knowledge, attitudes, and behaviors related to medication adherence.
  • To assess the scale's utility for pharmacist-led interventions.

Main Methods:

  • Literature review, expert consultation, and pilot survey informed scale development.
  • A convenience sample of 156 caregivers of children with recurrent respiratory infections was surveyed.
  • Psychometric analyses included item analysis, reliability (Cronbach's α, split-half), and validity (content, factor analysis).

Main Results:

  • The final 34-item scale demonstrated high reliability (overall Cronbach's α = 0.934) and validity (S-CVI = 0.902).
  • Seven dimensions were identified, explaining 73.617% of the variance.
  • The scale accurately reflects caregiver pharmacological readiness.

Conclusions:

  • The Pediatric Pharmacological Readiness Assessment Scale is a reliable and valid instrument.
  • It serves as a valuable tool for clinical pharmacists.
  • The scale can enhance discharge preparedness, improve medication adherence, and reduce readmissions for pediatric recurrent respiratory infections.

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