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Perioperative efficiency and clinical outcomes of single-port versus multi-port robot-assisted radical prostatectomy: an updated meta-analysis

  • 0The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China.
Journal of Robotic Surgery +

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August 18, 2025

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August 18, 2025

View abstract on PubMed

Summary

This summary is machine-generated.

Single-port (SP) robot-assisted radical prostatectomy (RARP) shows reduced blood loss, shorter hospital stays, and less pain compared to multi-port (MP) RARP. Both SP-RARP and MP-RARP offer similar oncologic and functional outcomes for prostate cancer patients.

Area Of Science

  • Urology
  • Surgical Oncology
  • Robotic Surgery

Background

  • The comparative efficacy of single-port (SP) versus multi-port (MP) robot-assisted radical prostatectomy (RARP) for prostate cancer is not well-established.
  • Conflicting evidence exists regarding perioperative outcomes, oncologic control, and functional recovery between SP-RARP and MP-RARP.

Purpose Of The Study

  • To systematically review and compare perioperative outcomes, oncologic efficacy, and functional recovery between SP-RARP and MP-RARP.
  • To synthesize current evidence on the relative benefits and drawbacks of each surgical approach for prostate cancer treatment.

Main Methods

  • A systematic literature search was performed across major databases (PubMed, Embase, Web of Science, Cochrane Library) for English-language studies up to June 2025.
  • Meta-analyses were conducted using R software (version 4.3.1), calculating weighted mean differences and odds ratios with 95% confidence intervals.
  • The review protocol was prospectively registered with PROSPERO (CRD420251114408).

Main Results

  • Patients undergoing SP-RARP demonstrated significantly lower estimated blood loss, shorter hospital stays, and earlier urinary catheter removal compared to MP-RARP.
  • SP-RARP was associated with reduced postoperative pain scores and lower opioid consumption during hospitalization and at discharge.
  • No significant differences were observed between SP-RARP and MP-RARP regarding functional outcomes (potency, continence), perioperative complications, positive surgical margins, biochemical recurrence, or operative duration.

Conclusions

  • Single-port robot-assisted radical prostatectomy offers significant advantages in minimizing intraoperative blood loss, expediting patient recovery, and enhancing postoperative pain management compared to multi-port RARP.
  • Despite a potentially longer operative time, both SP-RARP and MP-RARP yield comparable oncologic control and functional outcomes for prostate cancer patients.

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