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Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics
Published on: November 29, 2024
Lactate/albumin index as mortality predictor in abdominal sepsis
Ana L Bugarin-Arellano1, Luis R Ramírez-González1, Luis O Suárez-Carreón1
1Departamento de Cirugía General.
Objective:
To evaluate the predictive value of the lactate/albumin ratio (LAR) for mortality in patients with abdominal sepsis admitted to the intensive care unit (ICU).
Methods:
An analytical cross-sectional study to validate the diagnostic test for abdominal sepsis. Patients over 18 years old with a diagnosis of abdominal sepsis admitted to the ICU. The LAR was calculated in the first 24 hours of admission to the ICU to evaluate its prognostic value for mortality.
Results:
We included 85 patients diagnosed with abdominal sepsis. The main causes of abdominal sepsis are secondary to closed abdominal trauma with hollow organ injury in 22 patients (26%) and severe acute pancreatitis in 21 (25%) patients. The LAR was calculated with a cut-off point of 1.04 as a predictor of mortality for abdominal sepsis, with 90.6% sensitivity, 72.5% specificity, 66.5% positive predictive value and 92.75% negative predictive value.
Conclusions:
The LAR may be useful in patients with abdominal sepsis as a quick, easy, and inexpensive prognostic marker of mortality, compared to other scales that require multiple values for their performance.
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