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Related Experiment Video

Updated: Sep 11, 2025

Visualizing Scar Development Using SCAD Assay - An Ex-situ Skin Scarring Assay
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Visualizing Scar Development Using SCAD Assay - An Ex-situ Skin Scarring Assay

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Using adjuvant radiotherapy for keloid scars: a patient and observer assessment study.

Alice Santos-Alves1, Cláudia Franco-de Sá2, Pedro Soares1

  • 1Radiotherapy Department, Centro Hospitalar Universitário de São João, Porto.

Cirugia Y Cirujanos
|August 18, 2025
PubMed
Summary

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Adjuvant electron beam radiotherapy (RT) effectively reduces keloid recurrence after surgical excision. This treatment improves scar appearance and patient satisfaction with minimal adverse events.

Area of Science:

  • Dermatology
  • Radiation Oncology
  • Plastic Surgery

Background:

  • Keloids are benign fibroproliferative tumors resulting from abnormal wound healing.
  • Surgical excision is a common treatment, but recurrence rates can be high.
  • Adjuvant therapies are crucial for improving outcomes after keloid surgery.

Purpose of the Study:

  • To evaluate the efficacy of adjuvant electron beam radiotherapy (RT) in preventing keloid recurrence.
  • To assess the impact of RT on scar-related outcomes.
  • To determine patient satisfaction following combined surgical and RT treatment.

Main Methods:

  • Retrospective analysis of 32 patients with 36 keloid scars.
  • All patients underwent surgical excision followed by adjuvant electron beam RT.
Keywords:
Evaluación de cicatricesKeloidQueloideRadioterapiaRadiotherapyScar Assessment

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  • Scar assessment utilized the Patient and Observer Scar Assessment Scale post-treatment.

    • Main Results:

    • No major treatment-related adverse events were reported.
    • Significant correlations found between overall scar score and color, stiffness, thickness, and irregularity.
    • Electron beam RT demonstrated effectiveness in reducing keloid recurrence and improving scar quality.

    Conclusions:

    • Combined surgical excision and adjuvant RT is a highly effective treatment for keloids.
    • This approach leads to high patient satisfaction and low recurrence rates.
    • Adjuvant electron beam RT is a valuable therapeutic option for keloid management.