Related Experiment Video

Updated: Sep 11, 2025

Analysis of LINE-1 Retrotransposition at the Single Nucleus Level
11:52

Analysis of LINE-1 Retrotransposition at the Single Nucleus Level

Published on: April 23, 2016

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STING inhibits LINE-1 retrotransposition through sorting ORF1p to lysosomes for degradation

Yu Huang1,2, Fengwen Xu1,2, Lingwa Wang3

  • 1Key Laboratory of Pathogen Infection Prevention and Control (Ministry of Education), State Key Laboratory of Respiratory Health and Multimorbidity, National Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, P. R. China.

EMBO Reports
|August 18, 2025
PubMed

Keywords:
IFN-IndependentLINE-1LysosomeRetrotranspositionSTING

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