Toward the Search for Clinical and Cognitive Variables that Affect Employment in LATAM: a Multicenter Study.
Sandra Vanotti1,2, Michael Jaworski3, Oscar Daniel Ayala4,5
1INERE - Institute of Restorative Neurosciences, Buenos Aires, Argentina. svanotti@inere.com.ar.
Journal of Occupational Rehabilitation
|August 19, 2025
Summary
People with multiple sclerosis (PwMS) face significant employment challenges in Latin America (LATAM). Higher disability levels increase job loss, while accommodations are linked to self-awareness, SES, education, and physical disability.
Area of Science:
- Neurology
- Occupational Health
- Socioeconomics
Background:
- Rising unemployment and poor working conditions for people with multiple sclerosis (PwMS) in Latin America (LATAM) prompted the Quality-of-Life working group.
- Multiple Sclerosis (MS) significantly impacts employment, with a work-loss rate nearly three times higher than the general unemployment rate in LATAM.
Purpose of the Study:
- Describe occupational outcomes and employment status among PwMS in LATAM.
- Investigate the relationship between disability levels and employment status (ES).
- Quantify accommodation use and identify predictors of job accommodations.
Main Methods:
- Recruited 86 PwMS across five LATAM countries.
- Administered cognitive (BVMS, BICAMS), neuropsychological, depression (BDI-II), and fatigue (FSS) assessments.
- Collected socioeconomic status (SES) data and employment status information.
Main Results:
- 54.6% of PwMS were work-stable, 20.9% work-challenged, and 24.4% work-loss.
- Lower physical and cognitive disability levels correlated with stable employment.
- Job accommodations were predicted by self-awareness of cognitive impairment, higher SES, education, and physical disability.
Conclusions:
- Physical and neuropsychological disability increase the risk of work loss for PwMS.
- Self-awareness, SES, education, and physical disability are key factors in utilizing job accommodations.
- MS poses a substantial barrier to employment in LATAM, highlighting the need for targeted support and accommodations.
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