Related Experiment Video
Updated: Sep 11, 2025
Iris Fixation via External Pentagram Suturing
Published on: May 5, 2022
Preliminary assessment of the safety and effectiveness of artificial iris implantation
Si-Yi Wang1, Mi-Mi Liu2, Xi-Le Li2
1National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, Zhejiang Province, China.
Aim:
To preliminary explore the safety and effectiveness of artificial iris implantation.
Methods:
Fourteen patients with iris defects who underwent artificial iris implantation at Hainan Boao Super Hospital from June 2020 to September 2021 were retrospectively analyzed for safety and effectiveness of the surgery by comparing the preoperative and postoperative best-corrected visual acuity (BCVA), intraocular pressure (IOP), corneal endothelial cell density (ECD), ocular axial length (AL), anterior chamber depth (ACD), patient satisfaction of photophobia and appearance improvement, and postoperative complications.
Results:
The mean age was 37.21±14.85 (7-60)y, including 13 males and 1 female. The mean follow-up period was 4.64±2.32 (1-10)mo. The mean AL was 24.00±1.06 (21.68-25.58) mm. The postoperative mean anterior chamber depth measured was 4.07±0.75 (2.61-5.07) mm. The mean BCVA was 0.69±0.65 logMAR preoperatively and 0.46±0.60 logMAR at the last follow-up time (P=0.36). There was no significant differences in the IOP preoperative and postoperative (14.14±3.10 and 13.65±3.08 mm Hg, respectively, P=0.69). The preoperative ECD was 1674.09±566.11 per 1 mm2, and the postoperative ECD was 1439.45±425.15 per 1 mm2 (P=0.21). No obvious corneal opacity or corneal decompensation was observed in all patients. The preoperative and postoperative photophobia scores were 8.50±1.55 and 4.50±1.94, respectively (P<0.05), and the preoperative and postoperative appearance defect scores were 6.58±2.98 and 2.75±1.69, respectively (P<0.05). Among the 14 patients, one had artificial iris displacement, two had a transient IOP rise after treatment of antiglaucomatous eyedrops. No complications were observed during surgery.
Conclusion:
The novel artificial iris material is safe, which can significantly improve the appearance defects and photophobia, improve the postoperative visual acuity to a certain extent. This surgery had a high patient satisfaction rate with few and controllable postoperative complications. At the same time, the artificial iris, with its diverse configurations, variable colors, arbitrary cutting, and various surgical procedures, fully realizes personalized treatment, which solves the clinical problem of iris defect.
