Validation of the Turkish Version of the Questionnaire for Impulsive-Compulsive Disorders in Parkinson's...

Background: Impulse control disorders and related behaviors (ICDs-RBs) significantly affect the quality of life of Parkinson's disease (PD) patients. The Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease-Rating Scale (QUIP-RS) was developed to identify and monitor these behaviors. This study aimed to translate and validate the Turkish version of QUIP-RS. Methods: The translation process involved back-translation and expert review. Ninety-three patients with PD completed the Turkish QUIP-RS, Movement Disorder Society-Unified PD Rating Scale part III, Hoehn-Yahr stage, Standardized Mini-Mental State Examination, Frontal Assessment Battery, and selfreport tools for depression, anxiety, and impulsivity. Internal consistency, factor analysis, convergent and divergent validity were assessed, along with relationships between QUIP-RS domains, clinical features, and dopaminergic medication. Results: Eighty-seven patients were included in this analysis. The QUIP-RS's total Cronbach's alpha value was 0.925, demonstrating good reliability. Factor analysis showed a good model fit, reflecting different ICDs-RBs domains. Thirty-nine percent of the patients were screened with at least 1 ICDs-RB, 17.2% of participants had single ICDs-RBs, and 21.8% had multiple ICDs-RBs. The most prevalent ICDsRBs were punding, compulsive eating, and dopamine dysregulation syndrome (DDS). Total levodopa equivalent daily dose (LEDD) was related to only ICD-related behaviors (hobbyism, punding, DDS). In contrast, the dopamine agonist LEDD was significantly correlated with all ICDs-RBs except pathological gambling. Conclusion: ICD-RBs are common in the sample recruited fromTürkiye, and the Turkish version of the QUIP-RS is a valid and reliable tool for assessing ICD-RBs in Turkish-speaking groups.