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Medication Overuse Headache in the US: A National Cross-Sectional Survey
Naomi N Bailey1, Christopher M Herndon2, Timothy D Cruz3
1Boise VA Medical Center, Pharmacy, Boise, Idaho, USA.
Journal of Pain & Palliative Care Pharmacotherapy
|August 19, 2025
Summary
Many US adults are unaware of medication-overuse headache (MOH), even those who overuse headache medications. Patient education on MOH is crucial for effective headache management and prevention.
Area of Science:
- Neurology
- Public Health
Background:
- Medication-overuse headache (MOH) is a common cause of chronic headache.
- Understanding of MOH among the general adult population is not well-documented.
Purpose of the Study:
- To assess the awareness and understanding of medication-overuse headache (MOH) among adults in the United States.
- To identify potential gaps in patient knowledge regarding MOH and its associated risks.
Main Methods:
- A descriptive questionnaire with 18 items was administered to 329 adult participants in the US.
- Data collected included demographics, headache characteristics, medication usage, and awareness of the term 'medication-overuse headache'.
- Descriptive statistics and Mann-Whitney U tests were employed for data analysis.
Main Results:
- Nearly half of participants (47.1%) were aged 18-30 years.
- Tension-type headache was the most frequently reported diagnosis (43.8%).
- A significant proportion of respondents (26.7%) had never heard of medication-overuse headache, including some who reported overusing medications.
Conclusions:
- A considerable number of US adults, including those overusing headache medications, lack awareness of medication-overuse headache (MOH).
- Findings highlight a critical need for enhanced patient education on MOH to improve diagnosis and management.
- Targeted educational initiatives are recommended for patients experiencing frequent headaches and using analgesics or abortive medications.
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