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Predictive validity and cost-effectiveness analysis of two caries risk assessment tools for preschool children
Cheng Menglin1, Chen Yawen1, Yu Xingru1
1Department of Stomatology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Insights
The reduced Cariogram is more sensitive and cost-effective for preschooler caries screening than Cariostat. This simplified model aids community prevention programs, especially in resource-limited settings.
Area of Science:
- Pediatric Dentistry
- Public Health
- Dental Caries Prevention
Background:
- Community-based prevention programs require effective tools for caries risk screening in preschoolers.
- Evaluating the predictive validity and cost-effectiveness of screening tools is crucial for optimizing resource allocation.
Purpose of the Study:
- To compare the predictive validity and cost-effectiveness of Cariostat and a reduced Cariogram model for caries risk screening in 3-4 year old children.
- To inform the selection of appropriate tools for community-based dental caries prevention initiatives.
Main Methods:
- A 12-month longitudinal study involving 156 preschoolers (aged 3-4 years).
- Baseline caries risk assessment using Cariostat and a reduced Cariogram model.
- Follow-up oral examinations to record caries incidence and calculate predictive performance metrics (sensitivity, specificity, AUC).
- Cost-effectiveness analysis including cost per correctly identified moderate-to-high-risk child.
Main Results:
- 50.3% of children developed new caries over 12 months.
- The reduced Cariogram demonstrated higher sensitivity (90.24%) compared to Cariostat (73.17%).
- Specificity and AUC were similar between the two models.
- The reduced Cariogram was significantly more cost-effective, with a 6-fold lower cost per correctly screened child and a negative incremental cost-effectiveness ratio.
Conclusions:
- The reduced Cariogram model is superior to Cariostat for community-based caries screening in preschoolers, particularly regarding sensitivity and cost-effectiveness.
- Its higher sensitivity and lower cost make it a valuable tool for resource-limited settings.
- The findings support the implementation of the reduced Cariogram for guiding preventive dental strategies in early childhood.
Background:
This study compared the predictive validity and cost-effectiveness of Cariostat and a reduced Cariogram model for caries risk screening in preschoolers, to guide community-based prevention programs.
Methods:
A longitudinal study was conducted among 156 children (aged 3-4 years) recruited from two randomly selected kindergartens. Baseline assessments included oral examinations, caregiver questionnaires, and caries-risk stratification using Cariostat and the reduced Cariogram. After 12 months, follow-up examinations recorded caries incidence. Predictive performance was analyzed using sensitivity, specificity, and area under the receiver operating characteristic curve (AUC). Cost-effectiveness ratios (CER) and incremental cost-effectiveness ratio (ICER) were calculated per correctly identified moderate-to-high-risk child.
Results:
Among 147 children completing follow-up, 50.3% developed new caries (mean dmft increment: 1.41 ± 0.21). The reduced Cariogram showed higher sensitivity (90.24% vs. 73.17%) but similar specificity (43.08% vs. 44.62%) and AUC (0.71 vs. 0.69) compared to Cariostat. The cost per correctly screened moderate-to-high-risk child was 6-fold lower for the reduced Cariogram (¥14.41 vs. ¥82.68), with a negative ICER of -278.3 favoring the reduced Cariogram.
Conclusion:
The reduced Cariogram outperformed Cariostat in sensitivity and cost-effectiveness for community caries screening, despite modest specificity. Its lower cost and simpler implementation support use in resource-limited settings.
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