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Updated: Oct 15, 2026

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
Published on: April 23, 2019
Abstract:
Among 433 high school seniors, 12% were determined to be either polydrug users or abusers. In comparison to the non-polydrug users, polydrug users and abusers were significantly more likely to indicate: (1) physical abuse by and many conflicts with parents; (2) self-ratings of lazy, bored, rejected, and unhealthy, (3) serious suicidal thoughts, delinquent behavior, early use of marijuana and alcohol, and the tendency to drink more than six alcoholic drinks at a sitting; and (4) agreement with the following statements: "If something feels good, I usually do it and don't worry about the consequences" and "I try to play as much as possible and work as little as possible." These findings suggest that many polydrug users and abusers are either seeking pleasure or trying to escape pain. Because of the different reasons behind polydrug use, a variety of treatment and prevention strategies will be necessary to curb the polydrug problem among adolescents.
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