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Beyond the Imposter: Deciphering Capgras Syndrome and Multidisciplinary Management.
Manuel Glauco Carbone1,2, Tommaso Merati1, Rossella Miccichè1
1Department of Medicine and Surgery, Division of Psychiatry, University of Insubria, Varese, Italy.
Case Reports in Psychiatry
|August 20, 2025
Summary
This case report details a patient with Lewy body dementia (LBD) who developed Capgras syndrome (CS), experiencing delusions of imposters. Management involved medication and psychosocial support, showing partial improvement.
Area of Science:
- Neurology
- Psychiatry
Background:
- Capgras syndrome (CS) poses diagnostic challenges, especially when co-occurring with neurodegenerative diseases.
- Lewy body dementia (LBD) is characterized by cognitive decline, parkinsonism, and hallucinations.
Observation:
- A 73-year-old female with LBD developed CS, believing her deceased husband was an imposter.
- The patient exhibited sleep disturbances, cognitive decline, behavioral issues, and visual hallucinations.
Findings:
- Brain imaging and cognitive assessments were used for diagnosis.
- A treatment regimen including Lithium sulfate, Citalopram, and Lurasidone was implemented.
- Psychosocial interventions were integrated into the care plan.
Implications:
- Managing CS in LBD is complex, requiring personalized, multidisciplinary care.
- This case adds to the literature on CS in LBD, offering clinical insights.
- Further research is needed to optimize treatment strategies for this dual diagnosis.
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