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Updated: May 11, 2026

Stereotactic Radiosurgery for Gynecologic Cancer
Published on: April 17, 2012
[Advances in Radiotherapy in the Treatment of Metastatic Spinal Lesions]
Brian Guilherme Monteiro Marta Coimbra1, Alice Roxo Nobre de Souza E Silva2, Cauã Bhering Soares2
1Grupo de Coluna, Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brasil.
None:
Metastatic spinal disease has become increasingly common due to advances in systemic oncological therapies and the increase in the overall survival of cancer patients. Its treatment is palliative, but the meaning of this term has evolved and, today, consists of better and more effective condition control over longer periods. In the past, surgical and radiotherapy techniques, especially conventional external beam radiation therapy (cEBRT), were ineffective or morbid for controlling many types of tumors. Now, the emergence and advancement of stereotactic body radiation therapy (SBRT) drastically changed this scenario. Surgery for managing metastatic disease remains significant in radiotherapy-associated strategies, but its purpose and technique have undergone major updates. However, despite all technical advances, radiotherapy has toxicity and side effects that warrant consideration. In this article, we provide an updated review covering everything from history to innovations in treating spinal metastases, focusing on their benefits, indications, and clinical impact.
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