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Related Experiment Videos

Overripe ova and twinning.

S Harlap, S Shahar, M Baras

    American Journal of Human Genetics
    |November 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Late conception timing significantly increases twinning rates in orthodox Jewish women, suggesting a link to dizygotic twins. This finding holds across various demographics and reproductive health factors.

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    Area of Science:

    • Reproductive biology
    • Human genetics
    • Obstetrics

    Background:

    • Multiple births, including twins and triplets, have variable incidence rates.
    • Understanding factors influencing multiple gestation is crucial for reproductive health and outcomes.
    • Conception timing relative to ovulation may impact the likelihood of multiple births.

    Purpose of the Study:

    • To investigate the relationship between conception timing and multiple birth rates.
    • To determine if conception timing influences dizygosity versus monozygosity.
    • To analyze multiple birth rates in a specific population with estimated ovulation and conception dates.

    Main Methods:

    • Study conducted on a sample of orthodox Jewish women.
    • Estimation of ovulation day and earliest possible conception day for each participant.

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  • Calculation of twinning and triplet rates based on conception timing (early vs. late).

    • Main Results:

    • Overall twinning rate was 14.5/1,000 deliveries; triplet rate was 0.40/1,000.
    • Twinning rates were significantly higher in "late" conceptions (26.9/1,000) compared to "early" conceptions (11.4/1,000).
    • Triplet rates and unlike-sexed multiple sets also showed significant increases in late conceptions.

    Conclusions:

    • Late conception timing is strongly associated with an increased incidence of multiple births, particularly twins.
    • The excess of unlike-sexed twins in late conceptions suggests a potential link to dizygosity.
    • Other twinning mechanisms, such as polar body or uniovular dispermatic twinning, warrant consideration.