Twelve-Month Outcomes of Ultrasound Cycloplasty After Failed Glaucoma Surgery: A Prospective Study

UCP effectively reduced IOP by 54.10% in eyes with failed glaucoma surgeries after 12 months. Complete and qualified success rates were 21.05% and 68.42%, respectively, demonstrating UCP's potential as a safe and effective salvage treatment.

This prospective study aims to evaluate the outcomes and safety of ultrasound cycloplasty (UCP) in controlling intraocular pressure in patients with prior failed glaucoma surgeries.

A total of 19 eyes from 19 patients who underwent UCP following failed glaucoma surgery between September 2020 and September 2022, were included. All patients were followed for over 12 months. Intraocular pressure, ocular hypotensive medications, and best-corrected visual acuity were recorded and compared after surgery. Complete success was defined as intraocular pressure within the range of 6-21 mm Hg after treatment and a reduction of at least 20% from baseline, without the use of ocular hypotensive medications. Qualified success was defined the same as complete success but allows the presence of ocular hypotensive medications.

At 12 months follow-up, intraocular pressure decreased from 44.95±10.73 mm Hg to 20.63±6.19 mm Hg, representing a reduction of 54.10% ( P <0.01). The rates of complete successes and qualified successes were 21.05% (4 of 19 eyes) and 68.42% (13 of 19 eyes) 12 months after treatment, respectively.

UCP is an effective and safe surgical approach for eyes with prior failed glaucoma surgeries.