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Updated: Sep 10, 2025

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Symptom Recognition in Medical Conversations Via multi- Instance Learning and Prompt.
Hua Wang1, Xue-Feng Bai1, Xiu-Tao Cui2,3
1School of Mechatronic Engineering and Automation, Shanghai University, Shanghai, 200444, China.
This study introduces a new method for extracting symptoms from medical conversations using multi-instance learning and prompt-guided attention. The approach improves accuracy in electronic health record (EHR) generation by identifying specific symptom mentions in dialogue.
Area of Science:
- Natural Language Processing
- Medical Informatics
- Machine Learning
Background:
- Electronic health record (EHR) systems require automatic symptom extraction from medical dialogues.
- Challenges include scattered clues, informal language, and ambiguous/negated statements in patient descriptions.
- Existing models struggle with unstructured, multi-turn conversations.
Purpose of the Study:
- To develop a novel approach for fine-grained symptom identification in medical dialogues.
- To improve the accuracy and efficiency of automated medical record generation.
- To address challenges of scattered information, non-standard terminology, and negation in patient-reported symptoms.
Main Methods:
- A multi-instance learning (MIL) framework treats conversations as bags of utterances for improved recall.
- Prompt-guided attention leverages standardized terminology to recognize synonyms, implicit mentions, and negations, enhancing precision.
- R-Drop regularization is used to improve robustness against noisy data.
Main Results:
- The proposed method achieved an 85.93% F1-score, outperforming baselines by approximately 8%.
- Achieved 85.09% precision and 86.83% recall, demonstrating strong performance.
- Successfully identified specific symptom-utterance pairs, showcasing fine-grained extraction capabilities.
Conclusions:
- The combined MIL and prompt-guided attention approach effectively addresses challenges in symptom extraction from medical dialogues.
- This method enables precise symptom documentation, advancing automated medical information extraction and intelligent EHR systems.
- The fine-grained extraction supports diagnostic decision support and improves the quality of medical records.
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