Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Circadian Rhythms and Gene Regulation02:19

Circadian Rhythms and Gene Regulation

4.1K
The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent...
4.1K
Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

289
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
289
Cognitive Development During Adolescence01:18

Cognitive Development During Adolescence

129
During adolescence, individuals experience significant cognitive development that enhances their understanding of others' emotions and thoughts, known as cognitive empathy. This period is marked by an increased ability to adapt to others' perspectives and a more nuanced understanding of others' mental states, a skill that is foundational for social problem-solving and conflict avoidance. The development of cognitive empathy relies heavily on the theory of mind — the...
129
Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response01:15

Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response

124
Circadian rhythms are cyclic changes that are crucial in plasma drug concentrations. Various standard circadian parameters, including core body temperature, heart rate, and other cardiovascular factors, directly impact disease states and the therapeutic response to drug therapy.
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
124
Influence of Parents and Peers on Identity01:23

Influence of Parents and Peers on Identity

130
Adolescence is a pivotal period of identity formation, during which individuals begin to answer questions central to their sense of self, such as "Who am I?" and "Who do I hope to become?" Both parents and peers play critical roles in guiding adolescents through this complex developmental phase.
Parental Influence on Identity Development
Parents serve as primary guides and managers in an adolescent's life, offering support instrumental in decision-making and personal growth....
130
Depressive Disorders: Etiology01:27

Depressive Disorders: Etiology

166
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
166

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Test of the reward/circadian rhythm dysregulation model of risk for bipolar spectrum disorders at a micro time scale using multilevel moderated mediation.

Journal of psychopathology and clinical science·2026
Same author

Reward Sensitivity's Associations with Morningness-Eveningness and Other Circadian-Coupled Behavioral Phenomena: A Systematic Review and Meta-Analysis of Cross-Sectional and Prospective Relationships.

Clinical psychology : a publication of the Division of Clinical Psychology of the American Psychological Association·2026
Same author

Utility and validity of group atlas versus personalized functional network approaches for depressive constructs.

bioRxiv : the preprint server for biology·2026
Same author

The highs and lows: Cannabis use and positive valence bipolar mood and emotion processes in emerging adults.

Journal of affective disorders·2026
Same author

Sex-specific influences of prenatal inflammation on offspring psychological symptoms in late midlife.

Psychoneuroendocrinology·2026
Same author

Trait reward sensitivity and behavioral motivation are associated with connectivity between the default mode network and the striatum during reward anticipation.

Cognitive, affective & behavioral neuroscience·2026
Same journal

Adverse Childhood Experiences and Youth Sports Participation: Variations Across Demographic Characteristics.

Journal of youth and adolescence·2026
Same journal

From Social Status Insecurity to Popularity: Testing Bullying as a Strategy and Classroom Norms as a Moderator.

Journal of youth and adolescence·2026
Same journal

Reciprocal Relationships Between Perceived Teachers' Moral Grandstanding, Self-Esteem, and Rumination Among Chinese Primary School Students: An RI-CLPM Study.

Journal of youth and adolescence·2026
Same journal

The Hidden Majority: Dual-Factor Mental Health Profiles Among Help-Avoidant University Students.

Journal of youth and adolescence·2026
Same journal

Trajectories and Bidirectional Associations between Loneliness and Non-suicidal Self-Injury among Chinese Adolescents.

Journal of youth and adolescence·2026
Same journal

Loneliness and the Presence of Meaning: Co-Developmental Trends and Reciprocal Dynamics among Chinese Junior High School Students.

Journal of youth and adolescence·2026
See all related articles

Related Experiment Video

Updated: Sep 10, 2025

Author Spotlight: Understanding Adolescent Social Adversity Effects on Neurodevelopment in Mice
07:15

Author Spotlight: Understanding Adolescent Social Adversity Effects on Neurodevelopment in Mice

Published on: March 15, 2024

1.7K

Reward Sensitivity, Pubertal Development, and Circadian Rhythms: A Window into Adolescent Risk for Depressive

Mackenzie A Maddox1, Rachel F L Walsh1, Logan T Smith1

  • 1Department of Psychology and Neuroscience, Temple University, Philadelphia, PA, USA.

Journal of Youth and Adolescence
|August 20, 2025
PubMed
Summary
This summary is machine-generated.

Adolescent reward sensitivity and pubertal development are linked to disrupted circadian rhythms. This disruption, combined with reward sensitivity, predicts changes in depressive symptoms, offering insights into adolescent mental health.

Keywords:
AdolescenceCircadian rhythmsMood disordersReward sensitivity

More Related Videos

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents
06:55

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents

Published on: December 2, 2015

22.7K
The Unpredictable Chronic Mild Stress Protocol for Inducing Anhedonia in Mice
07:13

The Unpredictable Chronic Mild Stress Protocol for Inducing Anhedonia in Mice

Published on: October 24, 2018

17.7K

Related Experiment Videos

Last Updated: Sep 10, 2025

Author Spotlight: Understanding Adolescent Social Adversity Effects on Neurodevelopment in Mice
07:15

Author Spotlight: Understanding Adolescent Social Adversity Effects on Neurodevelopment in Mice

Published on: March 15, 2024

1.7K
An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents
06:55

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents

Published on: December 2, 2015

22.7K
The Unpredictable Chronic Mild Stress Protocol for Inducing Anhedonia in Mice
07:13

The Unpredictable Chronic Mild Stress Protocol for Inducing Anhedonia in Mice

Published on: October 24, 2018

17.7K

Area of Science:

  • Neuroscience
  • Developmental Psychology
  • Chronobiology

Background:

  • Pubertal maturation influences reward and circadian systems, potentially increasing psychopathology risk.
  • Understanding the interplay between reward sensitivity, circadian rhythms, and mental health during adolescence is crucial.

Purpose of the Study:

  • To examine the associations between trait reward sensitivity, circadian rhythms, pubertal development, and depressive symptoms in adolescents.
  • To investigate how these factors interact to predict changes in depressive symptoms.

Main Methods:

  • Utilized self-report questionnaires and one week of actigraphy for data collection.
  • Recruited 320 adolescents (average age 15.12, 57.5% female) from the Philadelphia area.

Main Results:

  • Higher reward sensitivity and greater pubertal maturity were associated with increased circadian rhythm disruption.
  • Circadian disruption and reward sensitivity levels predicted differential changes in depressive symptoms.

Conclusions:

  • The findings suggest a complex interplay between reward sensitivity, circadian rhythms, and pubertal development in the context of adolescent mental health.
  • These associations may contribute to understanding the onset and trajectory of depressive symptoms during adolescence.