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Updated: Sep 10, 2025

Modulating Cognition Using Transcranial Direct Current Stimulation of the Cerebellum
Published on: February 15, 2015
Inferior frontal gyrus is responsible for cognitive control during two-digit number processing: fNIRS evidence from
Yunfeng He1, Huan Zhang2, Hans-Christoph Nuerk3
1Liaoning Key Laboratory of Psychological Testing and Behavior Analysis, Liaoning University, Shenyang, China; Department of Psychology, University of Tuebingen, Tuebingen, Germany.
Abstract:
Cognitive control plays an indispensable role in multi-digit number processing. The place-value structure of multi-digit numbers is apparent when comparing numbers. If the comparison of units yields a different result from the comparison of decades, the process takes longer than comparing compatible number pairs. Behavioral and eye-tracking studies have shown that this unit-decade compatibility effect was larger under high as compared to low cognitive control demands. However, the question arises whether cognitive control operates mainly as a domain-general effect in the frontal cortex, or if it directly affects domain-specific number magnitude processes in the parietal cortex. In the current fNIRS study, cognitive control demands were manipulated by adjusting the proportion of within-decade fillers in two-digit number comparison tasks (N = 80). The compatibility effect was replicated, and the fNIRS results showed that cognitive control is associated with the inferior frontal gyrus in two-digit number comparison. Thus, cognitive control operates mainly in the frontal cortex and does not directly affect domain-specific number magnitude processes in the parietal cortex. Methodological and linguistic limitations are discussed. Overall, this neurocognitive evidence supports that domain-general cognitive processes are relevant for multi-digit number processing.
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