Related Experiment Video
Updated: Jul 13, 2026

09:02
Breast Milk Enhances Growth of Enteroids: An Ex Vivo Model of Cell Proliferation
Published on: February 15, 2018
19.5K
Increasing Pasteurized Donor Human Milk Use in a Level 1 Newborn Nursery
Giuseppina Romano-Clarke1,2, Ananya Jain3,4, Georgia Dey-Lawson1
1Department of Pediatrics, Massachusetts General Hospital, Boston, Massachusetts.
Hospital Pediatrics
|August 20, 2025
Summary
Supplementation with pasteurized donor human milk (PDHM) increased by 70% in a level 1 nursery. This initiative improved breastfeeding exclusivity at discharge and sustained exclusive breastfeeding at two months for many infants.
Area of Science:
- Neonatal care
- Lactation support
- Public health nutrition
Background:
- Formula supplementation in well newborns impacts breastfeeding exclusivity.
- Pasteurized donor human milk (PDHM) is an alternative to formula.
- Initiatives are needed to promote PDHM use in nurseries.
Purpose of the Study:
- To increase the use of PDHM instead of formula in well newborns by 10%.
- To improve breastfeeding exclusivity at hospital discharge.
Main Methods:
- Process analysis and provider surveys identified barriers to PDHM use.
- Interventions included staff education and improved PDHM accessibility.
- Plan-do-study-act cycles refined PDHM use into a standard workflow.
Main Results:
- PDHM use increased by 70% and was sustained for 12 months.
- Breastfeeding exclusivity at discharge rose from 49.2% to 57.2%.
- 54.5% of infants receiving PDHM remained exclusively breastfed at 2 months.
Conclusions:
- Addressing local barriers and stakeholder involvement are crucial for implementing PDHM.
- PDHM use during birth hospitalization supports longer breastfeeding exclusivity.
More Related Videos
Related Concept Videos
Pasteurization and Food Preservation
Pasteurization is a widely employed thermal processing technique designed to enhance the safety and shelf life of perishable food and beverages. By subjecting products to specific high temperatures for controlled durations, this method effectively inactivates pathogenic microorganisms and spoilage enzymes without significantly compromising sensory qualities. The technique has been pivotal in food safety management, especially for consumables susceptible to microbial contamination such as milk,...
Development of Human Microbiota
The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from the skin...

