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Updated: Sep 10, 2025

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Standardization, Education, and Resourcing: The Way Forward for Implementing Polygenic Risk Scores in Hereditary

Rebecca Purvis1,2, Natalie Taylor3, Mary-Anne Young4,5

  • 1Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia.

Clinical and Translational Science
|August 21, 2025
PubMed
Summary

Genetic healthcare providers in Australia support implementing polygenic risk scores (PRS) for hereditary breast and ovarian cancer (HBOC) risk assessment. Key priorities include education, standardization, and addressing resourcing and equity concerns for successful national adoption.

Keywords:
genetic healthcare providershereditary breast and ovarian cancerimplementation determinantspolygenic risk scoresstrategies and priorities

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