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Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

Microfluidic technologies for wearable and implantable biomedical devices.

Ziheng Wang¹, Ankit Shah², Hyowon Lee^2,3

¹School of Mechanical Engineering, Purdue University, West Lafayette, IN 47907, USA. lee2270@purdue.edu.

|August 21, 2025

Summary

Microfluidic technology in wearable devices enables real-time biofluid analysis for health monitoring and drug delivery. This review covers design, materials, fabrication, and future directions for advanced biomedical systems.

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Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

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Published on: September 19, 2017

Area of Science:

Biomedical Engineering
Materials Science
Nanotechnology

Background:

Microfluidic technologies are revolutionizing biomedical devices.
Wearable and implantable systems require precise biofluid control.
Soft, biocompatible materials are key for advanced health monitoring and therapeutics.

Purpose of the Study:

To review critical design considerations for microfluidic biomedical devices.
To examine material strategies and fluid handling mechanisms for performance and biocompatibility.
To explore fabrication techniques and applications in wearable and implantable healthcare.

Main Methods:

Systematic review of microfluidic fabrication methods (soft lithography, 3D printing, laser micromachining, textile-based).
Analysis of design considerations, material selection, and fluid handling.
Exploration of use cases and current challenges.

Main Results:

Microfluidics enables precise real-time biofluid analysis for continuous health monitoring.
Various fabrication methods offer distinct advantages for wearable and implantable applications.
Key applications include sweat analysis, diagnostics, and in vivo therapeutics.

Conclusions:

Microfluidic devices hold significant promise for personalized healthcare.
Future directions include bioresorbable materials, AI, and wireless integration.
Overcoming challenges in stability and power is crucial for clinical translation.