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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Intraocular Lens Position Stability During Phacovitrectomy with Air or Gas Tamponade.

Yuji Yoshikawa1,2, Takashi Matsushima2, Shunichiro Takano1

  • 1Department of Ophthalmology, Saitama Medical University, Iruma, Saitama, Japan.

Clinical Ophthalmology (Auckland, N.Z.)
|August 21, 2025
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Summary

The DIB00V intraocular lens (IOL) demonstrated superior stability during phacovitrectomy with air or gas tamponade. It showed greater resistance to displacement compared to other IOLs, ensuring excellent z-axis positioning.

Keywords:
anterior chamber depthdisplacementimplantationpostoperativeretinal surface

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Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Materials Science

Background:

  • Phacovitrectomy is a common surgical procedure.
  • Intraocular lens (IOL) stability is crucial for successful surgical outcomes.
  • Air or gas tamponade is frequently used in vitreoretinal surgery.

Purpose of the Study:

  • To evaluate the stability of different intraocular lenses (IOLs) after phacovitrectomy.
  • To compare the performance of DIB00V, XY-1, and NX70s IOLs under air or gas tamponade conditions.
  • To assess the impact of gas/air tamponade on anterior chamber depth and IOL position.

Main Methods:

  • Retrospective cross-sectional study of 28 patients.
  • Analysis of DIB00V, XY-1, and NX70s IOLs after phacovitrectomy with air or sulfur hexafluoride gas.
  • Anterior segment optical coherence tomography (AS-OCT) for ACD and IOL position measurements.
  • Verification experiment to measure IOL displacement force.

Main Results:

  • Anterior chamber depth (ACD) increased as gas decreased post-surgery for all IOLs.
  • DIB00V showed significantly larger ACD than XY-1 and NX70s under specific gas conditions.
  • All IOLs shifted posteriorly as gas disappeared; DIB00V and NX70s showed minimal change between 50% and 0% gas.

Conclusions:

  • The DIB00V IOL exhibited superior z-axis stability during phacovitrectomy with air or gas tamponade.
  • DIB00V demonstrated a greater displacement force compared to XY-1 and NX70s.
  • These findings suggest DIB00V is a stable option for IOL implantation in phacovitrectomy cases requiring gas or air tamponade.