Associated factors of spontaneous reperfusion in patients with acute ST-segment elevation myocardial infarction
Weimin He1, Yixuan Lin1, Fengxin Yuan1
1Department of Cardiology, The Sixth Affiliated Hospital, South China University of Technology, Foshan, China.
Background:
This is a retrospective analysis of the relationship between preoperative factors and spontaneous reperfusion (SR) in infarct-related arteries (IRAs) in patients with ST-segment elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention (PCI).
Methodology:
834 patients who were classified into the SR group (TIMI flow grade 2-3) and non-spontaneous reperfusion (NSR) group (TIMI flow grade 0-1) based on coronary angiography. The baseline characteristics and preoperative factors of the two groups were analyzed.
Results:
Compared with the NSR group, the SR group had shorter time from symptom onset to first medical contact (P=0.002) and from symptom onset to antiplatelet loading (P=0.003), however, there was no statistically significant difference in the mode of admission and loading of antiplatelet drugs between the two groups. Multivariate logistic regression analysis indicated that diabetes history, smoking history, triglyceride level, time from symptom onset to first medical contact, time from symptom onset to antiplatelet loading, and time from antiplatelet loading to coronary angiography were all factors influencing SR were all factors influencing SR.
Conclusion:
The occurrence of SR is related to early medical contact and timely use of antiplatelet drugs. Patients with diabetes history, smoking history, higher triglyceride level may benefit more.
More Related Videos
05:26Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
Published on: May 28, 2019
14:35Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs
Published on: April 17, 2021
Related Concept Videos
01:30Acute Coronary Syndrome I: Introduction
01:30Acute Coronary Syndrome III: Diagnostic Studies
01:28Acute Coronary Syndrome IV: Interprofessional Care
01:19Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
01:20Blood Studies for Cardiovascular System I: Cardiac Biomarkers
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...